The effect of hydrocortisone versus hydrocortisone plus fludrocortisone on duration of shock: A propensity score-weighted analysis.

Background: The 2021 Surviving Sepsis Campaign Guidelines recommend the use of hydrocortisone in patients who remain hemodynamically unstable despite adequate fluid resuscitation and vasopressor therapy. Fludrocortisone has been used concomitantly with hydrocortisone in some studies without a clearly defined role or known clinical benefit. The purpose of this study was to assess the impact of fludrocortisone added to hydrocortisone on shock-free days for septic shock.

Dirofilariasis Presenting as Orbital Abscess Complicating Ethmoid Sinusitis.

Dirofilariasis in deep tissue plane is seldom reported in literature. A 58 year old woman presented with right orbital abscess complicating ethmoid sinusitis. She underwent endoscopic ethmoidectomy with abscess drainage where a dirofilaria worm was extracted.

Impact of Adding Rapid Polymerase Chain Reaction-based Blood Culture Identification Panel to Antimicrobial Stewardship Program: Initial Experience.

Arjun R, Niyas VKM, John KE, Nair A, Hussain F. Impact of Adding Rapid Polymerase Chain Reaction-based Blood Culture Identification Panel to Antimicrobial Stewardship Program: Initial Experience. Indian J Crit Care Med 2022;26(10):1155-1157.

Removal of a 10-kb transposon from of cv. Chardonnay.

Many white grape cultivars have a nonfunctional gene due to the presence of a 10-kb transposon in its promoter. In this study, we successfully demonstrated removal of the 10-kb transposon and functional restoration of a allele in cv. Chardonnay through transgenic expression of Cas9 and two gRNAs simultaneously targeting two junction sequences between LTRs and .

. bacteremia outbreak related to contaminated furosemide ampoules.

Nosocomial outbreaks related to medication contamination are reported world-wide. A sudden increase in cases of spp. bacteremia led to an outbreak investigation in our setting.

Study of Lithium Silicide Nanoparticles as Anode Materials for Advanced Lithium Ion Batteries.

The development of high-performance silicon anodes for the next generation of lithium ion batteries (LIBs) evokes increasing interest in studying its lithiated counterpart-lithium silicide (LiSi). In this paper we report a systematic study of three thermodynamically stable phases of LiSi (x = 4.4, 3.

Long-term T-DNA insert stability and transgene expression consistency in field propagated sugarcane.

This study addresses T-DNA insert stability and transgene expression consistency in multiple cycles of field propagated sugarcane. T-DNA inserts are stable; no transgene rearrangements were observed. AmCYAN1 and PMI protein accumulation levels were maintained.

Genetic engineering of a Lemna isoleucine auxotroph.

Lemna, a member of the Lemnaceae or duckweed family, is a small aquatic plant that can be quickly transformed to produce recombinant proteins in a contained and controlled bioprocessing environment. The containment capability of Lemna has been further improved with the creation of an auxotroph platform that requires isoleucine supplementation for survival of transformed plant lines. Using an RNAi based approach, threonine deaminase (TD) expression was targeted and thus resulted in dramatically reduced expression of this key enzyme in the isoleucine biosynthesis pathway.