Publications by authors named "John Kave"
Background: The Lihir Islands of Papua New Guinea, located in an area with high burden of malaria and hosting a large mining operation, offer a unique opportunity to study transmission. There, we investigated human and vector factors influencing malaria transmission.
Methods: In 2019, a cross-sectional study was conducted on 2,914 individuals assessing malaria prevalence through rapid diagnostic tests (RDT), microscopy, and quantitative PCR (qPCR).
Article Synopsis
- Pneumonia is a major cause of death for young children worldwide, particularly in Papua New Guinea, prompting a study to identify clinical predictors of hypoxic pneumonia.
- The study involved observing 2067 children aged 0-4 with pneumonia, revealing that hypoxia was present in 36.1%, with key indicators including central cyanosis, reduced breath sounds, and nasal flaring.
- While the new predictive model was better than existing criteria, it still had limitations, highlighting the need for pulse oximeters in healthcare settings and the importance of certain clinical signs for managing severe cases without them.
Background: Pneumonia is a leading cause of childhood mortality with a major contributor. Pneumococcal conjugate vaccines (PCVs) have been introduced into immunisation programs in many low- to middle-income countries (LMICs) yet there is a paucity of data evaluating the effectiveness in these settings. We assess the effectiveness of 13-valent PCV (13vPCV) against hypoxic pneumonia, hospitalisation and other clinical endpoints in children <5 years living in Eastern Highlands Province, Papua New Guinea (PNG).
View Article and Find Full Text PDFBackground: Pneumonia and meningitis are common causes of severe childhood illness in Papua New Guinea (PNG). The etiology of both clinical conditions in PNG has not been recently assessed. Changes in lifestyle, provision and access to healthcare, antimicrobial utilization and resistance, and the national childhood vaccination schedule necessitate reassessment.
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