Age-dependent oral manifestations of neurofibromatosis type 1: a case-control study.

Introduction: Most craniofacial manifestations of neurofibromatosis type 1 (NF1) are considered as a result of tumor compression. We sought to determine salivary changes, caries, and periodontal complications in NF1 patients without tumors in the oral cavity.

Objective And Methods: Eleven NF1 patients without tumors in the oral cavity and 29 matched controls without NF1 were enrolled in this case-control study.

Patients with juvenile idiopathic arthritis are at increased risk for obstructive sleep apnoea: a population-based cohort study.

Background And Objectives: Juvenile idiopathic arthritis (JIA), an autoimmune disease, has been proposed to be comorbid with obstructive sleep apnoea (OSA). We aimed at testing the hypothesis that patients with JIA may presented with high risk of OSA in a cohort study.

Subjects And Methods: This is a cohort study including patients with JIA from 1999 to 2013 identified from a longitudinal health registry.

Fibromyalgia and periodontitis: Bidirectional associations in population-based 15-year retrospective cohorts.

Background: To determine the bidirectional link between periodontitis and fibromyalgia.

Methods: In this cohort study, 196,428 periodontitis patients and 196,428 propensity score-matched non-periodontitis controls were enrolled. A Cox proportional hazard model was utilized to estimate the risk of fibromyalgia and survival analysis was adopted to assess the time-dependent effect of periodontitis on fibromyalgia.