Background And Objective: Visual restoration therapy is a home-based treatment program intended to expand visual fields of hemianopic patients through repetitive stimulation of the borderzone adjacent to the blind field. We hypothesized that the training itself would induce visual field location-specific changes in the brain's response to stimuli, a phenomenon demonstrated in animal experiments but never in humans with brain injury.
Methods: Six chronic right hemianopic patients underwent functional magnetic resonance imaging (fMRI)--responding to stimuli in the trained visual borderzone versus the nontrained seeing field before and after 1 month of visual restoration therapy.