Critically ill adults can suffer from stress-related mucosal damage leading to upper gastrointestinal bleeding (UGIB), necessitating preventive measures in ICU settings.
A panel of 18 international experts developed evidence-based guidelines using the GRADE methodology to provide recommendations for reducing UGIB risk in adult ICU patients.
The panel's findings indicate several risk factors for UGIB, such as coagulopathy and shock, and recommend using proton pump inhibitors or histamine-2 receptor antagonists for at-risk patients, while emphasizing that enteral nutrition may help mitigate risk.
The relationship between prior fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection is unknown. Among 125 enrolled patients, 8.8% had H.