Publications by authors named "John J Araujo"

Article Synopsis
  • COVID-19 significantly affects coagulation in adult patients with congenital heart disease (ACHD), making them more susceptible to thromboembolic (TE) and bleeding complications.
  • In a study from May 2020 to November 2021 involving nearly 2,000 ACHD patients, 1.5% experienced severe TE or bleeding events, which were linked to higher mortality rates and more advanced health conditions.
  • Key risk factors for these complications included prior anticoagulation treatment, incidents of cardiac injury, and severity of the COVID-19 infection, with logistic regression confirming their independent associations with TE and bleeding risks.
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In 2020, there was an estimated prevalence of more than 1.8 million adults with congenital heart disease (ACHDs) living in South America, and 677,000 in Central America and the Caribbean. The ACHD mortality is higher in developing countries, compared with developed countries, and it has been shown that concentrating this population in specialized ACHD units improves their survival and prognosis.

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Background: In recent years, patient-reported outcomes (PROs) have received increasing prominence in cardiovascular research and clinical care. An understanding of the variability and global experience of PROs in adults with congenital heart disease (CHD), however, is still lacking. Moreover, information on epidemiological characteristics and the frailty phenotype of older adults with CHD is minimal.

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Background: Adults with congenital heart disease (CHD) have been considered potentially high risk for novel coronavirus disease-19 (COVID-19) mortality or other complications.

Objectives: This study sought to define the impact of COVID-19 in adults with CHD and to identify risk factors associated with adverse outcomes.

Methods: Adults (age 18 years or older) with CHD and with confirmed or clinically suspected COVID-19 were included from CHD centers worldwide.

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Background: Influenza vaccination (IV) and Pneumococcus vaccination (PV) are recommended for patients with cardiometabolic diseases. This study aimed to evaluate the immunization rate of ambulatory cardiometabolic patients during the COVID-19 pandemic in the Americas.

Methods: Electronic surveys were collected from 13 Spanish speaking countries between 15 June and 15 July 2020.

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Functional classification of children and adults with repaired and unrepaired congenital heart disease is a challenge for clinicians, due to the heterogeneity of congenital heart disease. Functional studies may be complemented with a stress echocardiogram, which analyzes the hemodynamic behavior of surgical repair zones, residuals, and sequelae. The integration of the anatomical and functional classification criteria developed for congenital heart disease and the results of a stress echocardiogram can establish a more precise functional classification.

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