Publications by authors named "John H Tranter"
Article Synopsis
- High-power, short-duration (HPSD) radiofrequency ablation (RFA) can shorten procedure times, but effectiveness and safety depend on catheter design and operating conditions.
- The study tested different RFA settings in swine to find the best parameters for using a new flexible-tipped, contact force-sensing catheter for creating effective lesions.
- Optimal settings were found to be 60-70 W of power for less than 8 seconds with a contact force of less than 15 g, leading to significant effectiveness in creating lesions during pulmonary vein isolation.
Background: Pulmonary vein isolation (PVI) ablation is a standard therapy for paroxysmal atrial fibrillation (PAF). Lesion Index (LSI) is a metric to guide radiofrequency (RF) ablation using the TactiCath Ablation Catheter, Sensor Enabled with the EnSite Cardiac Mapping System (Abbott).
Objective: This study (NCT-03906461) was designed to capture best practices using LSI-guided catheter ablation to treat PAF subjects in a real-world setting.
Background: Although lesion transmurality is required for durable pulmonary vein isolation, excess ablation is associated with increased risk of complications.
Objective: We sought to understand the impact of interrupted radiofrequency (RF) delivery conditions on lesion characteristics in the atrial free wall.
Methods: Thirty-three (11 left atrial, 22 right atrial) RF ablation lesions were created in the atria of 6 swine using power control mode (25 W, target contact force 15 g) with 1 of 3 conditions: 15 seconds ablation (n = 8), 30 seconds ablation (n = 14), or 2 15-second ablations at the same site separated by a 2-minute interruption (15 seconds × 2) (n = 11).
Background: During catheter ablation, delivery of radiofrequency (RF) energy to a target site is sometimes interrupted by catheter instability and clinical factors. The impact of interruption of RF delivery on lesion characteristics has not been characterized.
Objective: The purpose of this study was to determine the impact of interruption of RF application on lesion size.
Purpose: The optimal radiofrequency (RF) power and lesion duration using contact force (CF) sensing catheters for atrial fibrillation (AF) ablation are unknown. We evaluate 50 W RF power for very short durations using CF sensing catheters during AF ablation.
Methods: We evaluated 51 patients with paroxysmal (n = 20) or persistent (n = 31) AF undergoing initial RF ablation.