Leadless pacemakers: A review of current data and future directions.

Leadless pacemakers (LPs) have revolutionized the field of pacing by miniaturizing pacemakers and rendering them completelty intracardiac, hence reducing complications related to pacemaker pockets and transvenous leads. However, first generation LPs appear to be associated with a higher rate of myocardial perforation as compared to transvenous pacemakers (TV-PPM). Currently, LPs are predominantly designed to pace the right ventricle with no LPs that provide atrial or biventricular pacing.

Imaging for Predicting, Detecting, and Managing Complications After Transcatheter Aortic Valve Replacement.

The management of patients with valvular heart disease is increasingly reliant on multimodal cardiac imaging. In patients with severe aortic stenosis considered for transcatheter aortic valve replacement, careful pre-procedural planning with multimodal imaging is necessary to avoid and prevent complications during the procedure. During or immediately after the procedure, rapid echocardiographic assessment is important to assess the new valve's function and manage major complications.

Pulmonary Venous Waveforms Predict Rehospitalization and Mortality After Percutaneous Mitral Valve Repair.

Objectives: In this study, the authors hypothesized that intraprocedural improvement of pulmonary venous (PV) waveforms are predictive of improved outcomes. In this report, they analyzed intraprocedural invasive and echocardiographic changes with respect to rehospitalization and mortality.

Background: The effects of hemodynamic changes during percutaneous mitral valve repair (PMVR) with MitraClip (Abbott Vascular, Santa Clara, California) are incompletely characterized.

Cardiac events during treatment with proteasome inhibitor therapy for multiple myeloma.

Background: Proteasome inhibitors (PI) bortezomib and carfilzomib are cornerstone therapies for multiple myeloma. Higher incidence of cardiac adverse events (CAEs) has been reported in patients receiving carfilzomib. However, risk factors for cardiac toxicity remain unclear.

Three and Four Horizontal Muscle Surgery for Large Angle Exotropia.

Purpose: Surgery on two horizontal recti typically is most effective for angles less than 40 prism diopters (PD). The authors evaluate their experience operating on three or four rectus muscles for angles exceeding 40 PD.

Methods: Retrospective chart review of 47 patients who underwent a first surgical procedure for a large angle comitant exodeviation.

A Comparative Study of Two New Structure Types. Synthesis and Structural and Electronic Characterization of K(RE)P(2)Se(6) (RE = Y, La, Ce, Pr, Gd).

Two polytypes of potassium rare-earth-metal hexaselenodiphosphates(IV), K(RE)P(2)Se(6) (RE = Y, La, Ce, Pr, Gd), have been synthesized from the stoichiometric reaction of RE, P, Se, and K(2)Se(4) at 750 degrees C. Both single-crystal and powder X-ray diffraction analyses showed that the structures of these polytypes vary with the size of the rare earth metals. For the smaller rare-earth metals, Y and Gd, K(RE)P(2)Se(6) crystallized in the orthorhombic space group P2(1)2(1)2(1).