Publications by authors named "John Greenall"

There are well-established morbidities associated with preterm birth including respiratory, neurocognitive and developmental disorders. However several others have recently emerged that characterise an 'aged' phenotype in the preterm infant by term-equivalent age. These include hypertension, insulin resistance and altered body fat distribution.

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Article Synopsis
  • Preterm infants exhibit a distinct "aged" phenotype, which includes poorer metabolic health compared to term-born infants, necessitating ongoing health monitoring to identify potential long-term issues.
  • The study explores the hypothesis that preterm infants experience changes in telomere attrition rates, which could serve as a prognostic biomarker for health outcomes.
  • The article reviews existing research on telomere length analysis in preterm infants and evaluates the methods available for measuring telomere length.
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In the UK, diagnosis of syphilis among women of child-bearing age has more than doubled between 1999 and 2007, and each year, around ten cases of congenital syphilis have been reported. Doctors should, therefore, be aware of the potential presentation of congenital syphilis, a deadly disease yet curable when managed correctly. We present a rare case of a premature neonate of 29 weeks displaying manifold clinical signs of congenital syphilis acutely after delivery, including coagulopathy, hepatosplenomegaly, intraventricular ischaemic lesions and metaphyseal bone changes, not previously described in the literature at this age in the UK.

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