Publications by authors named "John G Ladas"

Purpose: To evaluate the accuracy of current intraocular lens (IOL) formulas and identify factors influencing mean error in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK) triple procedure, that is, DMEK combined with cataract extraction and IOL placement for concurrent Fuchs endothelial corneal dystrophy (FECD) and cataracts.

Design: Retrospective cohort study.

Subjects: 90 eyes with FECD undergoing uncomplicated DMEK triple procedure at Wilmer Eye Institute.

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Purpose: To assess the refractive accuracy of eight intraocular lens (IOL) formulas in eyes that underwent combined phacovitrectomy.

Methods: A retrospective chart review of 59 eyes that underwent uncomplicated phacovitrectomy between 2017 and 2020 at the Johns Hopkins Wilmer Eye Institute. Inclusion criteria were postoperative best corrected visual acuity of 20/40 or better within 6 months of surgery and IOL implantation in the capsular bag.

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Purpose: To evaluate the refractive accuracy of current intraocular lens (IOL) formulas and propose a modification in calculation of corneal power in eyes undergoing combined cataract extraction and Descemet membrane endothelial keratoplasty (DMEK).

Design: Retrospective cohort study.

Methods: Patients with Fuchs endothelial corneal dystrophy undergoing uncomplicated combined cataract surgery and DMEK at a single institution were included.

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Purpose Of Review: The subject of artificial intelligence has recently been responsible for the advancement of many industries including aspects of medicine and many of its subspecialties. Within ophthalmology, artificial intelligence technology has found ways of improving the diagnostic and therapeutic processes in cornea, glaucoma, retina, and cataract surgery. As demands on the modern ophthalmologist grow, artificial intelligence can be utilized to help address increased demands of modern medicine and ophthalmology by adding to the physician's clinical and surgical acumen.

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Purpose: To evaluate the refractive accuracy of current intraocular lens (IOL) formulas in eyes with keratoconus.

Design: Retrospective case series.

Methods: Preoperative optical biometry, Pentacam topography, and postoperative outcomes were collected from eyes with keratoconus that had uncomplicated cataract surgery between 2014 and 2018 at a single institution.

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Various machine learning techniques have been developed for keratoconus detection and refractive surgery screening. These techniques utilize inputs from a range of corneal imaging devices and are built with automated decision trees, support vector machines, and various types of neural networks. In general, these techniques demonstrate very good differentiation of normal and keratoconic eyes, as well as good differentiation of normal and form fruste keratoconus.

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Importance: Cataract surgery is the most common eye surgery. Calculating the most accurate power of the intraocular lens (IOL) is a critical factor in optimizing patient outcomes.

Objectives: To develop a graphical method for displaying IOL calculation formulas in 3 dimensions, and to describe a method that uses the most accurate and current information on IOL formulas, adjustments, and lens design to create one "super surface" and develop an IOL "super formula.

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Purpose: To evaluate the accuracy of intraocular lens (IOL) power calculations with A-constant optimization in Descemet's stripping automated endothelial keratoplasty (DSAEK) combined with cataract extraction and intraocular lens implantation (DSAEK triple procedure).

Design: Retrospective case series.

Participants: Thirty eyes of 22 patients with Fuchs' endothelial dystrophy who underwent the DSAEK triple procedure performed by a single surgeon.

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Purpose Of Review: Corneal refractive procedures have become increasingly popular over the past decade, allowing patients to have excellent uncorrected visual acuity and spectacle independence. As these individuals mature, many will eventually undergo cataract surgery. With the advances in modern cataract surgery and lens implant technology, particularly presbyopic intraocular lens implants, patients and physicians have greater expectations regarding visual outcomes and independence from glasses after cataract surgery.

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Diagnosis and management of intraocular inflammation involves the assessment of cells and protein levels ("flare") in the aqueous humor. These factors are difficult to quantify precisely on clinical examination alone. Laser flare-cell photometry provides an automated technique to quantify these factors objectively, and it has been used in a variety of research and clinical situations to assess anterior segment inflammation.

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