Publications by authors named "John E Pierce"

Purpose: Carers of people with aphasia face unique challenges. Research has demonstrated that these carers have a higher burden of care and more negative stroke-related outcomes in comparison to carers of stroke survivors without aphasia. The aim of this scoping review was to map the range of interventions for carers other than communication partner training and to examine their outcomes.

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Background: Currently, there are no agreed quality standards for post-stroke aphasia services. Therefore, it is unknown if care reflects best practices or meets the expectations of people living with aphasia. We aimed to (1) shortlist, (2) operationalise and (3) prioritise best practice recommendations for post-stroke aphasia care.

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Multi-Modality Aphasia Treatment (M-MAT) is an effective group intervention for post-stroke aphasia. M-MAT employs interactive card games and the modalities of gesture, drawing, reading, and writing to improve spoken language. However, there are challenges to implementation of group interventions such as M-MAT, particularly for those who cannot travel or live in rural areas.

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Article Synopsis
  • High-intensity therapy is recommended for chronic poststroke aphasia, but the impact of treatment-induced fatigue on rehabilitation outcomes is not well understood.
  • The study analyzed self-rated fatigue levels of 173 participants during two types of intensive aphasia therapies, comparing a higher intensity (30 hours in 2 weeks) with a lower intensity (30 hours in 5 weeks).
  • Results showed that fatigue levels increased only slightly each day after therapy, with no evidence of accumulating fatigue over the intervention period, suggesting that intensive therapy may not significantly raise fatigue for individuals with chronic aphasia.
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Background: Primary progressive aphasia (PPA) is a neurodegenerative condition characterised by a prominent and progressive deterioration in language abilities, which significantly impacts quality of life and interpersonal relationships. Speech and language therapy plays a crucial role in offering interventions. Group intervention is one mode of delivery that could benefit communication functioning and overall wellbeing of people with PPA (pwPPA) and their care partners.

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Article Synopsis
  • Speech and language interventions can improve word retrieval and communication quality for people with aphasia post-stroke, but their cost-effectiveness remains unclear.
  • A study compared two therapy types (CIAT-Plus and M-MAT) against usual care in 216 chronic aphasia patients, assessing costs, outcomes, and quality-adjusted life years over 12 weeks.
  • Results showed no significant cost differences among groups but suggested M-MAT was more favorable in many scenarios, highlighting the need for further analysis on therapy effectiveness and cost savings.
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Purpose: Images are a core component of aphasia assessment and intervention that require significant resources to produce or source. Text-to-image generation is an Artificial Intelligence (AI) technology that has recently made significant advances and could be a source of low-cost, highly customizable images. The aim of this study was to explore the potential of AI image generation for use in aphasia by examining its efficiency and cost during generation of typical images.

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Article Synopsis
  • Aphasia is a communication disorder often caused by brain injuries like strokes, impacting individuals' quality of life, leading researchers to explore AI solutions for better management and rehabilitation.
  • A scoping review of 77 studies was conducted to track the evolution of AI in aphasia, assessing its research objectives and technological advancements over time.
  • The findings showed a shift from automated assessments to AI-driven therapy and personalized systems, indicating significant opportunities to further integrate AI in aphasia rehabilitation for tailored patient care.
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  • High-intensity aphasia therapies like CIAT-Plus and M-MAT are effective but challenging to implement, so this study examined their feasibility and effectiveness at lower intensities.
  • In a Phase II trial with chronic aphasia participants, both therapies were tested at a reduced intensity of 6 hours per week for 5 weeks, compared to the original higher intensity.
  • Results showed high participation and completion rates, with positive effects on word retrieval and functional communication, indicating that lower intensity therapies are feasible, acceptable, and may be effective.
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The effect of treatment dose on recovery of post-stroke aphasia is not well understood. Inconsistent conceptualization, measurement, and reporting of the multiple dimensions of dose hinders efforts to evaluate dose-response relations in aphasia rehabilitation research. We review the state of dose conceptualization in aphasia rehabilitation and compare the applicability of 3 existing dose frameworks to aphasia rehabilitation research-the Frequency, Intensity, Time, and Type (FITT) principle, the Cumulative Intervention Intensity (CII) framework, and the Multidimensional Dose Articulation Framework (MDAF).

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Background: While meta-analyses confirm treatment for chronic post-stroke aphasia is effective, a lack of comparative evidence for different interventions limits prescription accuracy. We investigated whether Constraint-Induced Aphasia Therapy Plus (CIAT-plus) and/or Multimodality Aphasia Therapy (M-MAT) provided greater therapeutic benefit compared with usual community care and were differentially effective according to baseline aphasia severity.

Methods: We conducted a three-arm, multicentre, parallel group, open-label, blinded endpoint, phase III, randomised-controlled trial.

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Purpose: Recent evidence supports the benefit of intensive aphasia intervention programs for people with chronic aphasia, yet it is unclear if all participants can expect positive outcomes and for how long therapeutic gains last.

Methods: We systematically searched for studies investigating intensive interventions in chronic aphasia. To explore individual response rates and maintenance of therapeutic gains we carried out meta-synthesis by calculating and analysing the Standard Error of Measurement and Minimal Detectable Change metrics of six common outcome measures.

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Purpose: Intensive Comprehensive Aphasia Programs (ICAPs) were first described in 2013 with an international survey documenting 12 unique programs. ICAPs involve high dose intervention delivered in both group and individual settings, targeting communication across impairment, functioning, participation, and contextual domains. In this study, we aimed to investigate international growth in ICAPs.

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Purpose: Aphasia is a debilitating chronic acquired language disorder that impacts heavily on a person's life. Behavioural treatments aim to remediate language processing skills or to enhance communication between the person with aphasia and others, and a number of different treatments are efficacious. However, it is unclear how much of a particular treatment a person needs in order to optimise recovery of language and communication skills following stroke.

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Little is known about how the amount of treatment a person with aphasia receives impacts aphasia recovery following stroke, yet this information is vital to ensure effective treatments are delivered efficiently. Furthermore, there is no standard dose terminology in the stroke rehabilitation or aphasia literature. This scoping review aims to systematically map the evidence regarding dose in treatments for post-stroke aphasia and to explore how treatment dose is conceptualized, measured and reported in the literature.

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Optimizing intensity for aphasia treatment is a high priority research issue for people with aphasia, their families and clinicians, and could result in healthcare cost savings. An important aspect of intensity is the frequency of intervention, or how regularly treatment should be provided each week. While principles of neuroplasticity endorse massed practice, cognitive psychology has established superiority of distributed practice within normal learning.

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Purpose Multimodal therapy is a frequent term in aphasia literature, but it has no agreed upon definition. Phrases such as "multimodal therapy" and "multimodal treatment" are applied to a range of aphasia interventions as if mutually understood, and yet, the interventions reported in the literature differ significantly in methodology, approach, and aims. This inconsistency can be problematic for researchers, policy makers, and clinicians accessing the literature and potentially compromises data synthesis and meta-analysis.

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Aphasia is a significant cause of disability and reduced quality of life. Two speech pathology treatment approaches appear efficacious: multimodal and constraint-induced aphasia therapies. In constraint-induced therapies, non-verbal actions (e.

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Background: Alternating motion rate (AMR) and sequential motion rate (SMR) are tests of articulatory diadochokinesis that are widely used in the evaluation of motor speech. However, there are no quality normative data available for adults aged 65 years and older.

Aims: There were two aims: (1) to obtain a representative, normative dataset of diadochokinetic rates from adults aged 65 years and older; and (2) to examine the effects of age and gender on those rates.

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