Publications by authors named "John E Dobbs"

Article Synopsis
  • The study focuses on finding effective diagnostic thresholds for BNP and NT-proBNP in diagnosing acute heart failure (AHF) in patients over 75 years old, both with and without other health conditions.
  • Data was collected from 12,071 hospitalized patients over a decade, with 65.8% diagnosed with AHF; various NT-proBNP thresholds were identified, showing high positive predictive values (PPV) based on age and specific health conditions.
  • The research concludes that co-morbidities significantly impact natriuretic peptide thresholds for AHF diagnosis in older patients, indicating a need for tailored approaches in this demographic.
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Introduction Acute COVID-19 patients can suffer from chronic symptoms known as post-acute sequelae of SARS-CoV-2 infection (PASC). Point-of-care ultrasound (POCUS) is established in acute COVID, but its utility in PASC is unclear. We sought to determine the incidence of cardiac and pulmonary abnormalities with POCUS in patients with PASC in a COVID-19 recovery clinic.

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Objective: Chikungunya virus (CHIKV) causes persistent arthritis, and our prior study showed that approximately one third of CHIKV arthritis patients had exacerbated arthritis associated with exercise. The underlying mechanism of exercise-associated chikungunya arthritis flare (EACAF) is unknown, and this analysis aimed to examine the regulatory T-cell immune response related to CHIKV arthritis flares.

Methods: In our study, 124 Colombian patients with a history of CHIKV infection four years prior were enrolled and 113 cases with serologically confirmed CHIKV IgG were used in this analysis.

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