Publications by authors named "John D Jacob"

Background: There is a discussion amongst oncologic societies regarding the necessity of preoperative biopsy prior to resection in lung cancer. We aim to examine outcomes of segmentectomy with or without preoperative biopsy in non-small cell lung cancer (NSCLC) patients.

Methods: A retrospective cohort study was conducted utilizing the National Cancer Database.

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Background: The real-world safety of robotic resections after neoadjuvant chemoimmunotherapy remains poorly defined in patients with non-small cell lung cancer. Due to reported increased operative challenges after neoadjuvant immunotherapy, we aim to describe our early institutional experience and outcomes after robotic resection in this clinical context.

Methods: We performed a retrospective chart review of patients with non-small cell lung cancer who underwent a robotic lobectomy, comparing patients from June 1, 2022, through October 31, 2023, who were treated with neoadjuvant chemoimmunotherapy consistent with the Checkmate-816 protocol and a control group with upfront resection.

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Bronchopleural fistula (BPF) typically occurs in the weeks after lobectomy or pneumonectomy and rarely occurs years after a surgical procedure. Management of BPF can be challenging, especially when it manifests in a delayed fashion. The report presents a case of asymptomatic BPF and pleurocutaneous fistula in a patient with a remote history of right pneumonectomy and unusual anatomy.

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Background And Objectives: Invasive secretory breast carcinoma (SBC) is a rare subtype of breast malignancy.

Methods: Cases of SBC and infiltrating ductal carcinoma (IDC) from the National Cancer Database (1998-2011) were queried.

Results: Patients with SBC (n = 246) and IDC were identified (n = 1,564,068).

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