Publications by authors named "John C Ku"
Pseudoalteromonas bacteria are capable of degrading paralytic shellfish toxins.
Appl Environ Microbiol
November 2009
Article Synopsis
- Marine bacteria from blue mussels contaminated with paralytic shellfish toxins (PSTs) were tested for their ability to detoxify PSTs.
- Seven bacterial strains significantly reduced the toxicity of a toxic algal extract by 90% or more within three days.
- These strains showed high genetic similarity (99%) to known Pseudoalteromonas species, suggesting they are likely new strains of Pseudoalteromonas haloplanktis.
Bacteria isolated from the digestive tracts of blue mussels (Mytilus edulis) contaminated with paralytic shellfish toxins (PSTs) were screened for the ability to reduce the toxicity of a PST mixture in vitro. Bacteria were isolated on marine agar and grown in marine broth supplemented with a mussel extract and an algal extract containing PSTs (saxitoxin, neosaxitoxin, gonyautoxins 2 and 3, decarbamoyl-gonyautoxins 2 and 3 and C1/C2 toxins). Toxin levels were measured before and after 5d of incubation, using high performance liquid chromatography (HPLC) and reduction of overall toxicity verified by mouse bioassays.
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