Patellar tendon anterior cruciate ligament reconstruction in the high-demand patient: evaluation of autograft versus allograft reconstruction.

Purpose: This study sought to compare patient-reported and objective outcomes in high-demand patients after anterior cruciate ligament reconstruction with either patellar tendon allograft or autograft by use of a matched-pairs case-control experimental design.

Methods: Nineteen matched pairs were obtained based on gender (36.8% female patients), age (27.

In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage.

Background: Single intra-articular injections of local anesthetics are commonly used clinically. Recent in vitro studies have demonstrated chondrotoxic effects of local anesthetics, with the greatest emphasis on bupivacaine toxicity. This in vivo study was conducted to determine whether a single intra-articular injection of 0.

Optimizing CO2 normalizes pH and enhances chondrocyte viability during cold storage.

Fresh osteochondral allografts are an important treatment option for the repair of full-thickness articular cartilage defects. Viable chondrocytes within the transplanted tissue are considered important to maintaining matrix integrity. The purpose of this study is to determine whether an increase in pH decreases chondrocyte viability during cold storage and whether equilibration of Dulbecco's modified Eagle's medium (DMEM) in 5% CO(2) normalizes pH and increases chondrocyte survival during storage at 4 degrees C.

Lidocaine exhibits dose- and time-dependent cytotoxic effects on bovine articular chondrocytes in vitro.

Background: Intra-articular lidocaine is commonly used.

Purpose: This study was conducted to determine whether short-term exposures to 1% and 2% lidocaine are toxic to articular chondrocytes, whether this is due to pH, and whether an intact articular surface is protective.

Study Design: Controlled laboratory study.