Publications by authors named "John C Affeldt"
While airbags have saved many lives and are clearly beneficial overall, sodium hydroxide (NaOH) powder produced by the inflation reaction can cause significant alkali ocular injury if not irrigated promptly. Here we report a case of severe airbag related ocular alkali injury as a way to bring attention to the need for prompt ocular irrigation following motor vehicle accidents (MVA) with airbag deployment. A 47-year-old man was involved in a MVA with airbag deployment in a rural setting.
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- The study aimed to investigate if a specific mutation in the TGFBI gene is linked to a condition involving amyloid deposits in the cornea.
- Involving 8 patients, methods included slit lamp examinations, DNA analysis from buccal swabs, and sequencing the entire TGFBI gene to look for mutations.
- Results showed amyloid deposits in all patients and identified one new genetic variant; however, no known pathogenic mutations were found, indicating that TGFBI mutations are not the cause of this condition.