Publications by authors named "John Arlette"

The severe acute respiratory syndrome coronavirus 2 pandemic has necessitated enhanced protection against viral transmission among healthcare professionals, particularly relating to handwashing and personal protective equipment. Some of these requirements may persist for years to come. They bring associated concerns around skin hygiene and general care, with damage to the face and hands now a well-documented consequence among healthcare professionals.

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Soft Tissue Filler (STF) Therapy for cosmetic facial rejuvenation is associated with known complications. The manifestation of these known complications can lead to patients commencing civil litigation actions or making complaints to provincial regulatory authorities and alleging that the practitioner failed to obtain the patient's informed consent to the therapy. Data provided by the Canadian Medical Protective Association (CMPA) on medical-legal cases arising from the provision of STF therapy between 2005 and 2019 are presented.

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In the past few decades, minimally-invasive esthetic treatments and the use of injectable Hyaluronic Acid Gels and other filling agents to treat facial esthetics have increased dramatically. Although extremely rare, a filler can cause ocular and orbital ischemia by retrograde flow from the ophthalmic artery when injected in any of the anastomosis of the face. Once filler reaches the central retinal artery, blindness is inevitable, and no treatment is effective.

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Background: Over the past decade, new technologies, devices, and methods have been developed to assist in the diagnosis of cutaneous melanocytic lesions.

Objective: Our objective was to evaluate the performance of an augmented intelligence system in the assessment of atypical pigmented lesions.

Methods: Nine atypical pigmented lesions on 8 patients were evaluated prior to surgical removal.

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Background: CD34-positive plaque-like dermal fibroma (PDF) is a poorly characterised benign dermal neoplasm that has a wide differential diagnosis. It can be mistaken for other entities on superficial biopsy and be overtreated, leading to unnecessary worry and extensive surgery.

Objective: To report on an uncommon presentation of this entity, the histopathologic differential diagnosis of PDF, and a novel treatment method.

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Background: Mohs micrographic surgery (MMS) is an accepted treatment for nonmelanoma skin cancer and has an evolving role in melanoma.

Objective: To review oncologic outcomes of MMS and wide local excision (WLE) treatments for facial melanoma.

Methods And Materials: A retrospective review of patients with invasive melanoma of the face between 1997 and 2007 identified from the Alberta Cancer Registry (Canada) was performed.

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Background And Objectives: The face is a common site of melanoma occurrence. The purpose of this study was to examine the management and outcomes of patients with invasive melanoma of the face.

Methods: Patients with invasive melanoma of the face managed at our institution from 1997 to 2008 were retrospectively reviewed.

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Article Synopsis
  • This study looked at whether people with Parkinson's disease (PD) are more likely to have melanoma (a type of skin cancer) in North America.
  • They checked 2106 patients with PD and found that many had pigmented skin spots, and confirmed some cases of melanoma.
  • The results showed that people with PD had a higher chance of having melanoma compared to those without PD, suggesting that doctors should pay more attention to skin checks for PD patients.
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  • Superficial leiomyosarcomas (SLMSs) are rare skin tumors that present as nodules, and a review of 25 cases revealed that they can involve both the dermis and subcutaneous tissue.
  • Histological analysis showed that all cases tested positive for smooth muscle markers, but CD117 was consistently negative; notable features included epidermal hyperplasia and unique collagen patterns.
  • Poor prognostic factors were identified, including tumor size over 2 cm, high grade, and greater depth, indicating the need for careful diagnosis to avoid misclassification as benign.
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BACKGROUND Products instilled within or beneath the skin to improve its physical features are known as fillers. The position of the filler within the skin is one determinant of the end cosmetic result. OBJECTIVE The objective was to histologically determine the anatomic location of injected hyaluronic acid (HA) filler within nasolabial fold (NLF) skin.

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Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor with a high recurrence rate. The goal of this study was to review patients with DFSP treated by Mohs micrographic surgery (MMS) and to compare demographics and recurrence rates with cases in the literature treated by standard excision methods. Medical charts were used to evaluate patient and tumor characteristics, number of stages for tumor clearance, reconstructive methods used, and recurrence rate after MMS.

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Background And Objectives: The treatment of lentigo maligna (LM) and lentigo maligna melanoma (LMM) is challenging due to lesion location, size, patient age, and potential for recurrence and spread. The largest studies to date confirm that for melanocytic tumours, MMS provides high local control rates while minimizing tissue loss. Herein we report our local control rate for melanoma treated by MMS over a decade.

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Background: Metastatic basal cell carcinoma (MBCC) is defined as primary cutaneous basal cell carcinoma (BCC) that spreads to distant sites as histologically similar metastatic deposits of BCC. There are less than 300 reported cases of MBCC in the literature.

Methods: This article examines two cases of MBCC and provides a literature review of risk factors inherent in epidemiology, patient demographics, and the clinicohistopathological characteristics of primary and metastatic BCC lesions.

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Lentigo maligna (LM) and lentigo maligna melanoma (LMM) represent a character, histogenetic subclass of melanocytic malignancies. They often present with a prolonged phase of slow growth but once invasion has occurred, the prognostic features are identical to all other melanomas. These lesions occur primarily on the head and neck where they evolve from areas of pigmented staining to the more typical features identifiable with malignant melanomas on other skin surfaces.

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Squamous cell carcinoma in situ (SCCIS) of the skin is a problem commonly dealt with by dermatologists. The classic presentation, originally described by Bowen, is easily recognized, but presentation on some anatomical surfaces may be associated with less than typical features. Major aetiological factors for this disease are UV light, human papillomavirus infection and immunosuppression.

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Article Synopsis
  • The study looks at a special surgery called Mohs micrographic surgery, which helps remove skin cancer from the face while keeping as much healthy skin as possible.
  • Researchers treated 97 patients with facial melanoma and found that none had the cancer return after the surgery.
  • Most patients were healthy afterward, and the results showed that the surgery was very accurate in finding and removing all the cancer.
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