Publications by authors named "John Aboje"
Article Synopsis
- * A systematic review and meta-analysis of existing literature found a migraine prevalence of 16% among 7,768 participants in Nigeria, with higher rates in women and various common triggers identified, such as fatigue and emotional stress.
- * The conclusion stresses the urgent need for improved healthcare policies and treatment strategies, as many individuals experience inadequate pain relief and side effects from common migraine medications.
Article Synopsis
- * A review of studies from 2000 to February 2024 reveals that these conditions lead to significant memory and cognitive impairments in mothers and cognitive deficits in their children due to factors like placental issues and maternal stress.
- * The research calls for a better understanding of the causes and the development of early interventions to help improve cognitive health in affected mothers and children through a multidisciplinary approach.
Background: Excimer laser coronary angioplasty (ELCA) has evolved as a pivotal element in percutaneous coronary intervention (PCI), significantly influencing procedural efficacy and safety. This mini-narrative review explores ELCA's applications, focusing on its efficacy and clinical outcomes. BODY: A search of major databases identified studies from ELCA's inception.
View Article and Find Full Text PDFIschaemic stroke, a leading cause of global morbidity and mortality, necessitates effective biomarkers for enhanced diagnostic and prognostic stratification. MicroRNAs (miRNAs), particularly miR-210, have emerged as promising candidates due to their intricate regulatory roles in cellular responses to hypoxia and neuroprotective effects. This study explores the potential of miR-210 as a biomarker for ischaemic stroke, considering its expression patterns, regulatory functions and diagnostic/prognostic implications.
View Article and Find Full Text PDFThis review explores the immunomodulatory potential of Teplizumab and its impact on pancreatic β-cell function in T1D. Characterized by the autoimmune destruction of insulin-producing beta cells, T1D's management involves maintaining glycemic control through exogenous insulin. Teplizumab, a humanized monoclonal antibody targeting the CD3 antigen, has shown promise in delaying T1D onset and preserving residual β-cell function.
View Article and Find Full Text PDFProstate cancer, constituting a substantial portion of global cancer incidence and mortality, prompts a critical examination of potential modifiers, notably ejaculation frequency. This narrative review explores the complex relationship between ejaculation frequency and prostate cancer risk, addressing the paucity of consensus and the intricate interplay of factors. The evidence drawn from eleven studies with diverse methodologies reveals a complex understanding of this association.
View Article and Find Full Text PDFMalaria affects millions of lives annually, particularly in tropical and subtropical regions. Despite being largely preventable, 2021 witnessed 247 million infections and over 600,000 deaths across 85 countries. In the ongoing battle against malaria, a promising development has emerged with the endorsement by the World Health Organization (WHO) of the R21/Matrix-M Malaria Vaccine.
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