Publications by authors named "John A C Chalmers"

Article Synopsis
  • The study aimed to identify perioperative factors linked to prolonged mechanical ventilation (PMV) in patients undergoing elective primary coronary bypass surgery.
  • PMV was found in 215 out of 10,977 patients (1.96%), with key predictors including higher NYHA class, renal dialysis, older age, reduced lung function, and a high body mass index.
  • The research concluded that PMV negatively affects early and mid-term survival, but modeling risks for PMV remains challenging, even in lower-risk patient groups.
View Article and Find Full Text PDF

Objectives: Although the association between chronic obstructive pulmonary disease (COPD) and adverse surgical outcomes has been previously demonstrated, the impact of COPD severity on postoperative mortality and morbidity remains unclear. Our objective was to analyse the prognostic implication of COPD stages as defined by the Global Initiative for Chronic Obstructive Lung Disease.

Methods: Between September 1997 and April 2010, 13,638 patients undergoing first time isolated CABG were retrospectively reviewed, of whom 2421 patients were excluded due to lack of spirometry records or restrictive pattern on spirometry.

View Article and Find Full Text PDF

Objectives: There remain concerns about hospital outcomes in octogenarians being referred for coronary artery bypass grafting (CABG). Avoiding the use of cardiopulmonary bypass (CPB) may be an attractive option to improve early outcomes in this group of patients.

Methods: Between April 1997 and March 2010, 343 consecutive patients aged 80-89 years received isolated first time CABG.

View Article and Find Full Text PDF

Background: Trauma to the heart is usually rapidly fatal, but survival can be improved with timely and appropriate surgical management. However, certain injuries require specialist cardiothoracic surgical intervention.

Methods: Three patients with coronary artery lacerations treated by cardiac surgeons at remote hospitals are presented.

View Article and Find Full Text PDF

Objective: To assess the incidence and impact of Methicillin-resistant Staphylococcus aureus (MRSA) infections on cardiac surgery outcomes and to identify adverse outcome traits.

Methods: Retrospective analysis of prospectively collected data from cardiac surgical and microbiology databases between April 2000 and March 2005. The overall and yearly incidence of positive MRSA cultures was examined along with the distribution of clinical infections and the associated mortality.

View Article and Find Full Text PDF

Background: Diabetes is commonly regarded as a risk factor for mortality and morbidity after coronary artery bypass surgery.

Methods: Between April 1997 and December 2002, 6,033 consecutive patients underwent isolated coronary artery bypass surgery. Eight hundred and fourteen (13.

View Article and Find Full Text PDF

Objective: The relationship between the timing of intra-aortic balloon pump (IABP) support and surgical outcome remains a subject of debate. Peri-operative mechanical circulatory support is commenced either prophylactically or after increasing inotropic support has proved inadequate. This study evaluates the effect timing of IABP support on the 1-year survival of patients undergoing cardiac surgery.

View Article and Find Full Text PDF