Large areas of paddy fields in southern China have been contaminated by arsenic (As), which causes serious problems such as the reduction of grain yield and high As concentrations in brown rice. To test the possibility of using plant growth-promoting rhizobacteria (PGPR) to promote rice growth and decrease As accumulation in brown rice in such paddy fields, three As-resistant PGPRs (strains S6, S7 and S10) were isolated and incorporated into two rice cultivars (Zhendao 14 and Jianyou G2) grown in different environments. The results showed that all PGPRs promoted rice growth (grain yield increased by 10.
View Article and Find Full Text PDFThis study is to investigate the roles of muscarinic receptor 3 (M receptor) in the effect of penehyclidine hydrochloride (PHC) upregulated beta-arrestin-1 expression in lipopolysaccharide (LPS)-stimulated human pulmonary microvascular endothelial cell (HPMVEC). HPMVECs were transfected with a shRNA-containing plasmid that specifically targets M receptor mRNA. Cells were collected to measure F-actin contents, levels of intercellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), as well as changes of F-actin cytoskeleton arrangement by Laser scanning confocal.
View Article and Find Full Text PDFAntibiotics can have significant and long-lasting effects on the gastrointestinal tract microbiota, reducing colonization resistance against pathogens including Clostridium difficile. Here we show that antibiotic treatment induces substantial changes in the gut microbial community and in the metabolome of mice susceptible to C. difficile infection.
View Article and Find Full Text PDFAtrial fibrillation (AF) and venous thromboembolism (VTE) are the two most common medical conditions managed with anti-coagulation therapy. Not all the patients with decreased mobility or AF have a similar risk for thromboembolism. The risk factors for venous thromboembolism and thromboembolism associated with AF are described in various studies.
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