Comparison of Droperidol and Midazolam Versus Haloperidol and Lorazepam for Acute Agitation Management in the Emergency Department.

Background: Acute agitation accounts for up to 2.6% of visits to the emergency department (ED). To date, a standard of care for the management of acute agitation has not been established.

Examining the Efficacy of a Brief Cognitive-Behavioral Therapy for Chronic Pain (Brief CBT-CP) Group Delivered via VA Video Connect (VVC) Among Older Adult Veterans.

Objectives: To evaluate the effectiveness of a Brief CBT-CP Group delivered via VA Video Connect (VVC) among different age groups of Veterans with chronic noncancer pain being seen in primary care. A secondary aim was to evaluate participant characteristics of patients who completed vs. did not complete the group.

Enhancing the Mentoring Experience for Underrepresented Students.

Undergraduate research is a valuable experience that increases the likelihood of a STEM major to continue on to postgraduate training in their field. For students from groups underrepresented in the biomedical sciences, a strong mentoring relationship during this undergraduate period is a key component in preparing them for the next stage of their education and can have a significant influence on their ability to persist in the pipeline. Although the ideal scenario to increase the diversity of the biomedical workforce is to provide more BIPOC (Black, Indigenous, People of Color) faculty mentors for our undergraduates, we also need to develop strategies to provide strong mentoring experiences for our BIPOC students when those mentors are not in great number.

Impacts of the Coronavirus Pandemic on the Emotional and Physical Health of Older Adults Compared with Younger Cohorts.

Objectives: This study compared emotional and physical health and overall well-being related to social restrictions during the pandemic among older, middle-aged, and younger adults in the United States ( = 276).

Methods: Online surveys collected information on mental and physical health, as well as positive and negative impacts of the pandemic. One-way MANOVAs and hierarchical regressions were used to analyze data.

Top consumer uses of bestselling, single-ingredient vitamin and mineral supplements.

Objective: Vitamin and mineral supplements are widely used for self-care of a variety of medical conditions, but little is known about the specific conditions for which they are used. This study mined consumer product reviews to determine specific ways vitamin and mineral supplements are being used therapeutically.

Design/setting: A cross-sectional analysis of user reviews for top-selling, single-ingredient vitamin and mineral products from a popular online retailer was performed to identify the most frequently appearing words associated with medical conditions.

Eighteen new species of Oecetis McLachlan 1877 (Trichoptera, Leptoceridae) from New Caledonia.

Eighteen new species of Oecetis are described, diagnosed, and illustrated from New Caledonia: Oecetis amphora sp. nov., Oecetis ovula sp.

Baseline Characteristics of the 2015-2019 First Year Student Cohorts of the NIH Building Infrastructure Leading to Diversity (BUILD) Program.

Objective: The biomedical/behavioral sciences lag in the recruitment and advancement of students from historically underrepresented backgrounds. In 2014 the NIH created the Diversity Program Consortium (DPC), a prospective, multi-site study comprising 10 Building Infrastructure Leading to Diversity (BUILD) institutional grantees, the National Research Mentoring Network (NRMN) and a Coordination and Evaluation Center (CEC). This article describes baseline characteristics of four incoming, first-year student cohorts at the primary BUILD institutions who completed the Higher Education Research Institute, The Freshmen Survey between 2015-2019.

Description of 47 new species of the New Caledonian endemic caddisfly genus Ward & Schefter (Trichoptera, Ecnomidae).

New Caledonia has a rich Trichoptera fauna with over 200 known species, most of them endemic. The total diversity has been estimated as high as 300 to 600 species. The endemic genus Ward & Schefter (Ecnomidae, Trichoptera) includes 28 described species.

BUILDING INTEGRATED PATHWAYS TO INDEPENDENCE FOR DIVERSE BIOMEDICAL RESEARCHERS: PROJECT PATHWAYS.

Diversity of backgrounds and life experiences on scientific teams is known to lead to more innovative ideas and better scientific products. However, in the United States, the percentages of individuals from underrepresented racial and ethnic groups who obtain doctoral degrees in the Sciences continue to be significantly lower than their percentages in the population. This has resulted in the need for nation-wide initiatives to remedy this inequality, and consequently produce more productive teams of scientific minds.

All for One And One for All: Coordinating the Resources of Individual Student Research Training Initiatives in Biomedical Sciences at Xavier University of Louisiana.

Xavier University of Louisiana has a national reputation for producing science, technology, engineering, and mathematics (STEM) graduates who go on to obtain MD and PhD degrees. According to a 2013 National Science Foundation report, Xavier is ranked first in producing African American graduates who go on to receive life sciences PhD degrees, fifth in the nation in producing African American graduates who go on to receive science and engineering PhD degrees, and seventh in producing African American graduates who go on to receive physical sciences PhD degrees. Xavier is currently third among the nation's colleges and universities in the number of African American graduates enrolled in medical school, according to data compiled by the Association of American Medical Colleges, and ranked first in the number of African American alumni who successfully complete their medical degrees.

BUILDING INFRASTRUCTURE LEADING TO DIVERSITY PROGRAM AT XAVIER UNIVERSITY OF LOUISIANA, .

Xavier University of Louisiana (XULA) is the only historically Black and Catholic institution of higher education in the United States. XULA's mission focuses on "the promotion of a more just and humane society" by educating students in a diverse learning environment. Even though Xavier's reputation in the sciences attracts many of the best and brightest students in the nation, the University also continues to provide an excellent educational opportunity to many students who, due to socioeconomic disparities, lack the appropriate preparation for college.

Building integrated pathways to independence for diverse biomedical researchers: , the BUILD program at Xavier University of Louisiana.

Background And Purpose: Xavier University of Louisiana is a historically Black and Catholic university that is nationally recognized for its science, technology, engineering and mathematics (STEM) curricula. Approximately 73% of Xavier's students are African American, and about 77% major in the biomedical sciences. Xavier is a national leader in the number of STEM majors who go on to receive M.

Laparoscopic paraesophageal hernia repair is safe in elderly patients.

Background: Paraesophageal hernias (PEHs) occur frequently in the elderly. Patients may not be referred for repair due to age or concern for high operative morbidity and mortality. The aim of this study was to compare outcomes of PEH repair based on age.

Review of New Caledonian species of Oxyethira Eaton, with description of 17 new species, and new records for Hydroptila Dalman and Hellyethira Neboiss (Trichoptera, Hydroptilidae).

New Caledonian representation of the cosmopolitan genus Oxyethira Eaton is reviewed, with the description of new species bringing to 26 the total for the genus on the island. The species are referred to three subgenera: Trichoglene Neboiss (11 species), Pacificotrichia Kelley (13 species) and Dampfitrichia Ulmer (one species) and one species is unplaced to subgenus. A key is provided to Oxyethira species of New Caledonia.

Inquiry-based experiments for large-scale introduction to PCR and restriction enzyme digests.

Polymerase chain reaction and restriction endonuclease digest are important techniques that should be included in all Biochemistry and Molecular Biology laboratory curriculums. These techniques are frequently taught at an advanced level, requiring many hours of student and faculty time. Here we present two inquiry-based experiments that are designed for introductory laboratory courses and combine both techniques.

The age, ancestral distribution and radiation of Chimarra (Trichoptera: Philopotamidae) using molecular methods.

The phylogeny of Chimarra has previously been examined using morphological characters for a smaller subset of taxa and geographical representativeness. Here molecular data from three genes (COI, CAD and POL-II) are used to reconstruct the phylogeny of the genus. The results show Chimarra to be monophyletic, and that some of the sister groups are paraphyletic.

Seven new species of Chimarra (Trichoptera: Philopotamidae) from Malawi.

For the first time species of caddisflies in the genus Chimarra Stephens 1829 are reported from Malawi. The following new species are described: Chimarra zombaensis, C. flaviseta, C.

Review of the New Caledonian species of Acritoptila Wells, 1982 (Trichoptera, Insecta), with descriptions of 3 new species.

We review the New Caledonian representatives of the Australasian endemic hydroptiline genus Acritoptila, based on examination of a considerable collection of material in the Swedish Museum of Natural History and of types of previously established species. A key for identification of males is given and includes 3 species newly described here: A. parallela sp.

Urgent laparoscopic repair of acutely symptomatic PEH is safe and effective.

Background: Acute incarceration of paraesophageal hernias (PEHs) requiring urgent or emergent surgery is rare. Patients are often elderly with significant comorbidities and have historically been treated with open abdominal or thoracic incisions. Our study was designed to evaluate the feasibility, safety, and efficacy of laparoscopic paraesophageal hernia repair (LPEHR) in patients with PEH and acute gastric volvulus.

Purification and characterization of enzymes from yeast: an extended undergraduate laboratory sequence for large classes.

Providing a project-based experience in an undergraduate biochemistry laboratory class can be complex with large class sizes and limited resources. We have designed a 6-week curriculum during which students purify and characterize the enzymes invertase and phosphatase from bakers yeast. Purification is performed in two stages via ethanol precipitation and anion exchange chromatography, and students perform both direct and coupled enzyme assays.

The New Caledonian genus Caledonotrichia Sykora (Trichoptera, Insecta) reviewed, with descriptions of 6 new species.

The New Caledonian endemic hydroptilid genus Caledonotrichia Sykora (Trichoptera) is reviewed and 6 new species are described: Caledonotrichia bifida, Caledonotrichia capensis, Caledonotrichia minuta, Caledonotrichia ouinnica, Caledonotrichia sykorai and Caledonotrichia vexilla. Together with the established species for which revised diagnoses are given, these raise to 11 the number of species known in this genus. The new species, females of 3 species, and several unusual larval cases are examined and described for further insight into relationships of this enigmatic genus.

Development of a high-throughput screen to detect inhibitors of TRPS1 sumoylation.

Small ubiquitin-like modifier (SUMO) belongs to the family of ubiquitin-like proteins (Ubls) that can be reversibly conjugated to target-specific lysines on substrate proteins. Although covalently sumoylated products are readily detectible in gel-based assays, there has been little progress toward the development of robust quantitative sumoylation assay formats for the evaluation of large compound libraries. In an effort to identify inhibitors of ubiquitin carrier protein 9 (Ubc9)-dependent sumoylation, a high-throughput fluorescence polarization assay was developed, which allows detection of Lys-1201 sumoylation, corresponding to the major site of functional sumoylation within the transcriptional repressor trichorhino-phalangeal syndrome type I protein (TRPS1).

Magadacerina, a new genus of Leptoceridae (Trichoptera) from Madagascar.

Magadacerina forcipata, new genus, new species (Trichoptera: Leptoceridae), is described from Madagascar. The monotypic genus is characterised by having the tibial spur formula 2,2,2; wings with sessile bifurcation of M; genitalia with preanal appendages fused with segment IX and greatly produced posterad, and a tergum X with an anteriorly extended ventral base articulating with a sclerotised spine-like process of the phallic shield. The new genus is most closely related to Blyzophilus in the tribe Blyzophilini.

Description of three new Triaenodes species from Fiji (Trichoptera, Leptoceridae).

THE FOLLOWING THREE NEW SPECIES ARE ILLUSTRATED AND DESCRIBED FROM FIJI: Triaenodes rebellus Eriksson & Johanson, sp. n., Triaenodes oscitus Müller & Johanson, sp.