The aim of this study was to determine whether horses exhibiting unilateral hindlimb lameness unload (rest) the lame limb more than the contralateral limb. The resting/unloading of the hindlimbs and the time spent lying down were measured using accelerometers. Ten non-lame horses and 20 lame horses were recruited for participation and monitored for 11 h overnight with accelerometers (MSR145, sampling rate: 1 Hz, and measuring range: ±15 g) attached to the lateral metatarsal and metacarpal regions of each limb.
View Article and Find Full Text PDFBackyard chickens often suffer from foot pad dermatitis (FPD), a condition exacerbated by poor husbandry, nutritional deficiencies, and obesity. Pressure-relieving bandages, commonly used in the treatment of FPD, are impractical for outdoor chickens as they quickly become wet and dirty, necessitating daily changes that are often unfeasible. This retrospective study explores the use of custom-fit silicone shoes created via 3D-printed molds as an alternative to traditional bandages.
View Article and Find Full Text PDFBackground: The bedside diagnosis of acute pulmonary edema is challenging. This study evaluated the breath-by-breath information from electrical impedance tomography (EIT), respiratory mechanics and volumetric capnography (VCap) to assess acute pulmonary edema induced by xylazine administration in anesthetized sheep.
Objective: To determine the ability and efficiency of each monitoring modality in detecting changes in lung function associated with onset of pulmonary edema.
Conventional plate osteosynthesis of critical-sized bone defects in canine mandibles can fail to restore former functionality and stability due to adaption limits. Three-dimensional (3D) printed patient-specific implants are becoming increasingly popular as these can be customized to avoid critical structures, achieve perfect alignment to individual bone contours, and may provide better stability. Using a 3D surface model for the mandible, four plate designs were created and evaluated for their properties to stabilize a defined 30 mm critical-size bone defect.
View Article and Find Full Text PDFObjective: To evaluate the impact of a 30% end-inspiratory pause (EIP) on alveolar tidal volume (V), airway (V) and physiological (V) dead spaces in mechanically ventilated horses using volumetric capnography, and to evaluate the effect of EIP on carbon dioxide (CO) elimination per breath (Vcobr), PaCO and the ratio of PaO-to-fractional inspired oxygen (PaO:FiO).
Study Design: Prospective research study.
Animals: A group of eight healthy research horses undergoing laparotomy.
Lying is a high priority behavior for dairy cows. As the quality of cubicles can influence their lying time, the interest in finding objective methods to assess the quality of floors has increased substantially over recent decades. This study aimed to evaluate a technical device for measuring elastic properties of floors for the application to bedding materials for cows.
View Article and Find Full Text PDFElectrical impedance tomography (EIT) is a non-invasive real-time non-ionising imaging modality that has many applications. Since the first recorded use in 1978, the technology has become more widely used especially in human adult and neonatal critical care monitoring. Recently, there has been an increase in research on thoracic EIT in veterinary medicine.
View Article and Find Full Text PDFBit configuration and acting rein forces play a crucial role in oral health and comfort of ridden horses. Although it is a big animal welfare issue, dynamic response of horses to different bits has yet not been thoroughly investigated. This convenience sample experimental study describes a model to overcome the almost uncontrollable influence of riders on rein tension and evaluates self-controlled maximum side rein tension of ten sound horses randomly bitted with a double-jointed (DJS) and a version of a Mullen mouth snaffle-bit under unridden conditions.
View Article and Find Full Text PDFObjective: In EIT applications to the thorax, a single electrode plane has typically been used to reconstruct a transverse 2D 'slice'. However, such images can be misleading as EIT is sensitive to contrasts above and below the electrode plane, and ventilation and aeration inhomogeneities can be distributed in complex ways. Using two (or more) electrode planes, 3D EIT images may be reconstructed, but 3D reconstructions are currently little used in thoracic EIT.
View Article and Find Full Text PDFObjective: To evaluate the penetration depth (VNPD) of 2 disposable Veress needles (VN) at 4 insertion sites in the abdomen.
Study Design: Descriptive study.
Sample Population: Canine cadavers (n = 22, 6 for confirmation of the test methods and 16 for the comparative study).
The arterial to end-tidal CO difference (PCO) and alveolar dead space fraction (VDalv = PCO/PaCO), are used to estimate Enghoff's "pulmonary dead space" (V/Q), a factor which is also influenced by venous admixture and other pulmonary perfusion abnormalities and thus is not just a measure of dead space as the name suggests. The aim of this experimental study was to evaluate which factors influence these CO indices in anesthetized spontaneously breathing horses. Six healthy adult horses were anesthetized in dorsal recumbency breathing spontaneously for 3 h.
View Article and Find Full Text PDFMeniscal pathologies are among the most common injuries of the femorotibial joint in both human and equine patients. Pathological forces and ensuing injuries of the cranial horn of the equine medial meniscus are considered analogous to those observed in the human posterior medial horn. Biomechanical properties of human menisci are site- and depth- specific.
View Article and Find Full Text PDFObjective: To compare two methods of Bohr-Enghoff physiological dead space to tidal volume ratio (Vd/Vt) determination using a mixing chamber and an E-CAiOVX metabolic monitor.
Study Design: Prospective, clinical, method-comparison study.
Animals: Twenty horses anaesthetized for elective orthopaedic procedures.
Objective: The aim of this study was to evaluate the effect of continuous positive airway pressure (CPAP) on regional distribution of ventilation and dead space in anaesthetized horses.
Study Design: Randomized, experimental, crossover study.
Animals: A total of eight healthy adult horses.
The aim was to examine the effects of recumbency and anaesthesia on distribution of ventilation in beagle dogs using Electrical Impedance Tomography (EIT). Nine healthy beagle dogs, aging 3.7±1.
View Article and Find Full Text PDFObjective: To evaluate three routinely used tidal volumes (V; 10, 12 and 15 mL kg) for controlled mechanical ventilation (CMV) in lung-healthy anaesthetized dogs by assessing alveolar ventilation (VT) and dead space (DS).
Study Design: Prospective, randomized clinical trial.
Animals: A total of 36 client-owned dogs.
Objective: To compare design features and mechanical properties of 13 commercially available Veress needles (VN).
Study Design: In vitro biomechanical study.
Sample Population: Veress needles from 9 manufacturers (6 reusable, 6 disposable, and 1 with a reusable stylet combined with a disposable cannula) were included in the study.
Objective: To examine changes in the distribution of ventilation and regional lung compliances in anaesthetized horses during the alveolar recruitment manoeuvre (ARM).
Study Design: Experimental study in which a series of treatments were administered in a fixed order on one occasion.
Animals: Five adult Warmblood horses.
Background: Intermittent hypoxia may occur in a number of clinical scenarios, including interruption of myocardial blood flow or breathing disorders such as obstructive sleep apnea. Although intermittent hypoxia has been linked to cardiovascular and cerebrovascular disease, the effect of intermittent hypoxia on the human heart is not fully understood. Therefore, in the present study, we compared the cellular responses of cultured human adult cardiac myocytes (HACMs) exposed to intermittent hypoxia and different conditions of continuous hypoxia and normoxia.
View Article and Find Full Text PDFObjective: To compare breathing patterns and transdiaphragmatic pressure during total intravenous (TIVA) and isoflurane anaesthesia in ponies.
Study Design: Experimental, cross-over study.
Animals: Six healthy ponies weighing 286 (233-388) ± 61 kg, age 13 (9-16) ± 3 years.
Objective: Previous studies showed an influence of xylazine on the LiDCO sensor in vitro and in standing horses, but did not prove that this interaction caused error in LiDCO measurements. Therefore, agreement of cardiac output (CO) measurements by LiDCO and bolus-thermodilution (BTD) was determined in horses receiving xylazine infusions.
Study Design: Prospective, experimental study.
Introduction: The use of alveolar recruitment maneuvers during general anaesthesia of horses is a potentially useful therapeutic option for the ventilatory management. While the routine application of recruitments would benefit from the availability of dedicated large animal ventilators their impact on ventilation and perfusion in the horse is not yet well documented nor completely understood.
Case History: A healthy 533 kg experimental horse underwent general anaesthesia in lateral recumbency.
Objective: To determine the skin temperature of the metacarpus in horses associated with the use of bandages and tendon boots, compared with the bare limb, at rest and after 20 minutes of lunging.
Animals: 10 adult horses.
Procedures: Skin temperature on the bare metacarpus of both forelimbs was measured at rest and after lunging.
Objective: We describe and test a novel device for large animal anaesthesia monitoring that uses standard human medicine spirometry sensors.
Study Design: In-vitro study.
Methods: The device consists of two adapters that enable the flow to be split evenly into four tubes in parallel, each tube containing a D-lite sensor.
Objective: To assess effects of camera angle and distance on measurement and reproducibility of thermographically determined temperatures of the distolateral aspect of the forelimbs in horses.
Design: Evaluation study.
Animals: 10 adult horses.