Publications by authors named "Johannes Josef Tebbe"
Fair allocation of funding in multi-centre clinical studies is challenging. Models commonly used in Germany - the case fees ("fixed-rate model", FRM) and up-front staffing and consumables ("up-front allocation model", UFAM) lack transparency and fail to suitably accommodate variations in centre performance. We developed a performance-based reimbursement model (PBRM) with automated calculation of conducted activities and applied it to the cohorts of the National Pandemic Cohort Network (NAPKON) within the Network of University Medicine (NUM).
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- The study investigates the prevalence and predictors of post-COVID-19 condition (PCC) symptoms in patients infected with SARS-CoV-2 variants delta and omicron.
- A total of 758 patients were analyzed, revealing that fatigue was the most common PCC symptom, with no significant difference in prevalence between delta and omicron infections at the three-month follow-up.
- Most patients reported stable health-related quality of life, with over two-thirds experiencing no decline, indicating that PCC is a common issue for both variants in the German population.
The German government initiated the Network University Medicine (NUM) in early 2020 to improve national research activities on the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic. To this end, 36 German Academic Medical Centers started to collaborate on 13 projects, with the largest being the National Pandemic Cohort Network (NAPKON). The NAPKON's goal is creating the most comprehensive Coronavirus Disease 2019 (COVID-19) cohort in Germany.
View Article and Find Full Text PDFA previously symptomless 86-year-old man received the first dose of the BNT162b2 mRNA COVID-19 vaccine. He died 4 weeks later from acute renal and respiratory failure. Although he did not present with any COVID-19-specific symptoms, he tested positive for SARS-CoV-2 before he died.
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