Publications by authors named "Johannes Huber"

Article Synopsis
  • The study examines bladder stone treatment trends in Germany from 2006 to 2020, focusing on data from a national hospital billing database.
  • The number of therapeutic interventions for lower urinary tract stones rose significantly, with transurethral cystolithotripsy (TUCL) becoming the most commonly performed procedure.
  • While TUCL's popularity increased, the overall use of open cystolithotomy and the combination of TUCL with prostate resection saw a decrease, indicating shifts in treatment practices.
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  • The study investigates the management of IVC tumor thrombus in renal cell carcinoma patients and aims to establish a minimum annual caseload for better surgical outcomes.
  • Researchers analyzed data from 2006-2020, revealing that hospitals performing at least 8 procedures annually had significantly lower in-hospital mortality rates (2.8%) compared to those with fewer than 8 cases (6.2%).
  • Factors influencing mortality included patient age, ventilation time, and hospital caseload, highlighting the importance of experience and volume in surgical success.*
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Background And Objective: With advancement in technology, it has been possible to use minimally invasive surgical approaches for performing pyeloplasty for the treatment of ureteral strictures. This study aims to investigate the current trends of pyeloplasty and reconstructive ureteral procedures.

Methods: We analyzed the nationwide German hospital billing database (Destatis) from 2006 to 2022.

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Introduction: We report a progressive treatment of a 31-year-old patient with end-stage renal disease secondary to congenital posterior urethral valve and valve bladder syndrome. He underwent a laser ablation of the urethral valve at the age of six, but on continuance of renal function deterioration ultimately a bilateral ureterocutaneostomy (UC) in the left lower abdomen had to be fashioned as a supravesical urinary diversion.

Case Presentation: For the management of dialysis dependent end-stage renal disease, an allogenic renal transplantation was planned.

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Article Synopsis
  • Robot-assisted kidney transplantations have been happening in Europe since 2015, with Germany starting to adopt the technique in urological centers.
  • The text discusses a specific case in Germany involving a 60-year-old patient who received a post-mortem robot-assisted kidney transplant.
  • The findings suggest that this method is a safe and effective way to combine traditional open surgery techniques with the benefits of minimally invasive surgery.
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Acute kidney injury (AKI) is a frequent and challenging clinical condition associated with high morbidity and mortality and represents a common complication in critically ill patients with COVID-19. In AKI, renal tubular epithelial cells (TECs) are a primary site of damage, and recovery from AKI depends on TEC plasticity. However, the molecular mechanisms underlying adaptation and maladaptation of TECs in AKI remain largely unclear.

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Purpose: To delineate the current trends regarding gender-affirming surgeries (GAS) in Germany.

Methods: Analysis of German hospital quality reports from 2006 to 2022 was conducted using the reimbursement.info tool.

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Background: Studies have shown insufficient utilization of care for patients with erectile dysfunction (ED) after radical prostatectomy (RP).

Aim: The aim of this study was to evaluate variables associated with barriers to seeking and receiving ED treatment.

Methods: In this multicenter prospective cross-sectional study, the functional outcomes of 936 patients were assessed 10 to 15 years after RP.

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  • The human papillomavirus (HPV) is a common sexually transmitted virus linked to various diseases, and vaccination is encouraged, but awareness and vaccination rates in Germany are low.
  • A nationwide online survey conducted between June 2019 and January 2024 assessed HPV knowledge among German students, focusing on their demographics and understanding of HPV transmission, vaccination effectiveness, and related issues.
  • Results showed 459 participants, mainly medical students, with significant gaps in HPV knowledge, including misconceptions about cancer cases associated with HPV and the protection offered by the vaccination for both boys and girls.
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Introduction: The number of urodynamic studies (UDS) has been declining steadily in recent decades, yet the reasons behind this trend remain poorly understood. This study aims to investigate the structural aspects of UDS in urology and explore the factors contributing to this decline.

Material & Methods: We surveyed all urological departments performing UDS as well as a representative sample of private practices in Germany in 2023.

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Background: The last decades revealed new scientific knowledge regarding the fertility and potential malignancy of undescended testis AQ2(UDT). Accordingly, many guidelines changed their recommendation concerning timing of therapy, with the goal of an earlier time of surgery.

Methods: We analyzed the number of new diagnosis and performed surgeries in predefined age groups provided by the obligatory annual reports of German hospitals in the reimbursement.

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Background: Stress urinary incontinence in men is predominantly iatrogenic after radical prostatectomy or transurethral interventions. Current studies show that there is a deficit in the availability of surgical therapy not only in Germany. The aim of this study is to investigate in more detail the structural health care situation of surgical treatment of male stress incontinence in Germany.

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Purpose: Despite many efforts, no reliable urinary marker system has so far shown the potential to substitute cystoscopy. Measuring volatile organic compounds (VOCs) from urine is a promising alternative. VOCs are metabolic products which can be measured from the headspace of urine samples.

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Purpose: An abnormal lower urinary tract poses significant challenges for transplant surgeons. Besides the ureteral anastomosis to an ileal conduit, there are diverse complex reconstructive solutions. Due to its rarity, standardization and teaching of complex urinary diversion is extremely difficult.

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Objective: To evaluate the nationwide online decision aid 'Entscheidungshilfe Prostatakrebs' (established in 2016, >11.000 users and 60 new users/week) for patients with non-metastatic prostate cancer (PCa), from the perspective of patients and urologists.

Patients And Methods: To provide personalised information, the tool collects most of the International Consortium for Health Outcomes Measurement standard set, personal preferences, psychological features, and a validated rating of the tool.

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Purpose: The Eurotransplant Senior program allocating grafts from donors ≥ 65 years to recipients aged ≥ 65 years has proven good results within the last 20 years. However, "old" grafts are also allocated to younger recipients < 65 years, and this outcome of "old for young" kidney transplantations (KT) still lacks detailed investigations.

Methods: All "old for young" KT performed at four tertiary referral centers were retrospectively compared including a recent follow-up, stratifying for "old for young" (donor ≥ 65 years to recipient < 65 years) vs.

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Purpose: Kidney transplantation (KT) is the most frequently performed organ transplantation. In Germany, KT is performed in urology and surgery departments with unknown consequences of this parallel structure. The aim of the study was to compare the development and outcome of KT in urology and surgery departments.

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Background: In addition to the objectifiable treatment quality, patients' perspectives are gaining relevance.

Objective: This study aimed to characterize available hospital rating websites (HRW) with regards to patient ratings and to compare them with data from hospital quality reports and quality assurance based on routine data (QSR) for urological departments.

Materials And Methods: After a structured online search for HRWs, websites were compared based on patient ratings from the 10 urologic departments with the largest intervention rates in 2021 using generalized estimated equations.

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Many people want to die at home, but it is often not possible because they do not share their wishes with family members. This study was conducted to find out the extent to which patients with advanced urological malignancies had wishes regarding their final stage of life, made arrangements accordingly, and communicated their wishes to relatives and health care professionals. We conducted a survey among advanced urological tumor patients during their clinic visit at a German university hospital using a 31-item questionnaire.

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Introduction: Vaccination against human papillomavirus (HPV) significantly reduces the risk for malignant diseases like cervix, anal, or penile cancer. However, although vaccination rates are rising, they are still too low mirroring a lack of disease awareness in the community. This study aims to evaluate knowledge about HPV vaccination as well as the vaccination rate among German medical students.

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Article Synopsis
  • Testicular tumors are the most common cancers in young men, and their treatment often includes the implantation of a testicular prosthesis during orchiectomy, yet little data exists on this trend in Germany.
  • Over a 15-year study period (2006-2021), the number of testicular prosthesis implantations in Germany rose from 699 to 870 cases, with notable shifts in reasons for implantation: a decrease in cases due to testicular tumors and an increase related to gender-affirming surgery.
  • Despite an overall increase in prosthesis implantations, a significant portion of hospitals performed very few surgeries (less than 5) consistently over the years, indicating a concentration of procedures in a limited number of facilities.
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  • This study analyzes trends in surgical methods, hospital stay length, and mortality rates for kidney transplants (KT) and living donor nephrectomies (LDN) in Germany from 2006 to 2021.
  • Key findings show a decrease in open LDN procedures from 82% to 22%, with laparoscopic methods rising significantly, while robotic LDN began to emerge.
  • Overall, living donor KT had a shorter hospital stay compared to donations after brain death, and in-hospital mortality rates were low, though caution is advised due to the rare deaths of healthy donors following LDN.
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  • - YouTube hosts a vast array of videos on radical prostatectomy, but a study aimed to evaluate their quality and usefulness for both patients and doctors, revealing a mixed picture regarding the reliability and medical content of these videos.
  • - Analyzing 179 selected videos from a total of 3,520 search results, researchers found that while the overall technical quality was high and reliability was good, the medical content was generally low and in need of careful vetting.
  • - The study highlights the varying benefits of YouTube videos on this topic, emphasizing the necessity for preselection to ensure patients receive accurate medical information, as there was no observed link between video views and scientific quality.
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The aim of this study was to investigate trends in selective internal radiation therapy (SIRT) for hepatocellular carcinoma (HCC), cholangiocarcinoma (CCC), and liver metastasis in Germany. We analyzed the nationwide German hospital billing database from 2006 to 2019 for the diagnosis of HCC, CCC or liver metastasis in combination with SIRT. For analyses of SIRT on the hospital level, we used the reimbursement.

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