Publications by authors named "Johannes Hoch"
Front Immunol
October 2023
Article Synopsis
- Serotonin deficiency due to lack of the serotonin transporter (SERT) is linked to metabolic changes and increased inflammation in mice, particularly when fed a high-fat diet.
- Research involved comparing SERT-deficient mice with wild-type mice over 19 weeks to assess body weight, insulin resistance, and inflammation levels in adipose tissue.
- Results indicated that SERT-deficient mice exhibited greater insulin resistance, liver issues, and higher levels of inflammatory markers in their adipose tissue compared to the wild-type, suggesting a connection between SERT deficiency and heightened inflammation in response to a high-fat diet.
