Sensory-Induced Human LTP-Like Synaptic Plasticity - Using Visual Evoked Potentials to Explore the Relation Between LTP-Like Synaptic Plasticity and Visual Perceptual Learning.

Objective: Stimulus-selective response modulation (SRM) of sensory evoked potentials represents a well-established non-invasive index of long-term potentiation-like (LTP-like) synaptic plasticity in the human sensory cortices. Although our understanding of the mechanisms underlying stimulus-SRM has increased over the past two decades, it remains unclear how this form of LTP-like synaptic plasticity is related to other basic learning mechanisms, such as perceptual learning. The aim of the current study was twofold; firstly, we aimed to corroborate former stimulus-SRM studies, demonstrating modulation of visual evoked potential (VEP) components following high-frequency visual stimulation.