Publications by authors named "Johannes Heinrich Spille"

Article Synopsis
  • Periodontitis is linked to systemic chronic inflammatory diseases, but there's limited understanding of how anti-cytokine therapies affect periodontal health and microbiome in such patients.
  • This study involved 13 patients, assessing their periodontal status and gingival fluid before and 14 weeks after starting anti-cytokine treatment, with a focus on changes in the microbiome.
  • Results showed a significant increase in microbial diversity, suggesting improvement in periodontal health, indicating a need for further research on the effects of biological treatments on periodontal conditions.
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The aim of the current study was to test the technical and clinical feasibility of a robotic system and investigate its potential in the surgical repair of perforated Schneiderian membranes using an ex-vivo porcine model. Eight pig heads were operated conventionally via a surgical loop and eight pig heads with the surgical robot "Symani Surgical System" (Medical Microinstruments, Inc., Pisa, Italy).

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Background: The aim of the current study was to comparatively assess the primary stability of different Straumann® implant designs (BLX, Straumann Tapered Effect, Bone Level Tapered, and Standard Plus) via resonance frequency analysis by using an implant insertion model in freshly slaughtered bovine ribs with and without cortical bone. Tapered Effect (4.1 × 10 mm), Bone Level Tapered (4.

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