Kidney embolization induces prompt organ response in a 86-year-old patient with MGRS-related AL-amyloidosis.

Despite substantial improvements following the introduction of novel agents and antibodies, amyloid light-chain (AL)-amyloidosis still carries a grim prognosis. Here, we report on the case of a severely frail 86-year-old patient suffering from monoclonal gammopathy of renal significance (MGRS)-associated AL-amyloidosis with a diuretic-refractory nephrotic syndrome. In this patient, treatment with bortezomib-dexamethasone effectively induced a serological response, but was unfortunately poorly tolerated and failed to promote renal recovery fast enough to prevent secondary complications.

Survey among nephrologists in Germany: current practice and management of pregnant women on dialysis .

Background: To assess the experience and practice patterns of nephrologists in Germany with regard to the care of pregnant women on dialysis.

Methods: The 26-item internet survey sent by email asked for demographic information, subjective proficiency, maternal and fetal complications, treatment approaches and goals.

Results: Of the 2,015 surveys sent out, 200 (10%) were available for evaluation.