Machine learning classification of mediastinal lymph node metastasis in NSCLC: a multicentre study in a Western European patient population.

Background: [F] FDG PET-CT has an important role in the initial staging of lung cancer; however, accurate differentiation between activity in malignant and benign intrathoracic lymph nodes on PET-CT scans can be challenging. The purpose of the current study was to investigate the effect of incorporating primary tumour data and clinical features to differentiate between [F] FDG-avid malignant and benign intrathoracic lymph nodes.

Methods: We retrospectively selected lung cancer patients who underwent PET-CT for initial staging in two centres in the Netherlands.

Noninvasive mapping of left ventricular electromechanical asynchrony by three-dimensional echocardiography and semi-automatic contour detection.

A system for analyzing left ventricular (LV) electromechanical asynchrony based on transesophageal 3-dimensional echocardiography (3-DE) and semi-automatic endocardial contour detection is described. Eighteen consecutive patients underwent 3-DE. Using TomTec 4DLV software, a 3-dimensional endocardial surface was reconstructed throughout the cardiac cycle.

Early identification of left ventricular remodelling after myocardial infarction, assessed by transthoracic 3D echocardiography.

Aims: The usefulness of 3D echocardiography (3DE) for accurate evaluation of left ventricular (LV) remodelling after acute myocardial infarction (AMI), and early identification of remodelling in the subacute phase, was assessed.

Methods And Results: Thirty-three AMI patients (21 anterior AMIs) underwent 3DE prospectively at baseline (6+/-4 days) and at 3, 6, and 12 months post-AMI. Remodelling was defined as >20% increase in end-diastolic volume (EDV) at 6 or 12 months in relation to baseline.

Quantification of left ventricular volumes and ejection fraction using freehand transthoracic three-dimensional echocardiography: comparison with magnetic resonance imaging.

Objectives: Our aim was to validate 3-dimensional echocardiography (3DE) for assessment of left ventricular (LV) end-diastolic volume, end-systolic volume (ESV), stroke volume, and ejection fraction (EF) using the freehand-acquisition method. Furthermore, LV volumes by breath hold-versus free breathing-3DE acquisition were assessed and compared with magnetic resonance imaging (MRI).

Methods: From the apical position, a fan-like 3DE image was acquired during free breathing and another, thereafter, during breath hold.

Importance of transducer displacement and tilting on three-dimensional echocardiographic volume assessment using apical or off-axis rotational acquisition: an in vitro study.

Objective: The goal of this study was to assess effects of translation (horizontal displacement) and angulation (transducer tilting) on 3-dimensional (3D) echocardiographic volumes of both balloons and human left ventricles after autopsy.

Methods: Six water-filled (non-) aneurysmatic balloons of 150, 250, and 350 mL and 3 hearts of different sizes and shapes were suspended upright in a water bath. Angulation and/or translation was performed respectively by tilting the transducer with a mechanical arm in a vertical plane relative to the balloon tip or true apex of the hearts and by shifting the water bath in the same vertical plane.