Fall Risk Assessment in Acute Rehabilitation: Comparison of Two Assessment Tools.

Purpose: Many fall risk assessment tools exist. However, few of these fall risk assessment tools have been tested in the acute rehabilitation setting. The purpose of our study was to compare the accuracy of the Hendrich II Fall Risk Model (HIIFRM) and Sunnyview Test Scale in predicting falls.

Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis.

There is an urgent need in multiple sclerosis (MS) patients to develop biomarkers and laboratory tests to improve early diagnosis, predict clinical relapses, and optimize treatment responses. In healthy individuals, the transport of proteins across the blood-brain barrier (BBB) is tightly regulated, whereas, in MS, central nervous system (CNS) inflammation results in damage to neuronal tissues, disruption of BBB integrity, and potential release of neuroinflammatory disease-induced CNS proteins (NDICPs) into CSF and serum. Therefore, changes in serum NDICP abundance could serve as biomarkers of MS.

Body fluid biomarkers in multiple sclerosis: how far we have come and how they could affect the clinic now and in the future.

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system, which affects over 2.5 million people worldwide. Although MS has been extensively studied, many challenges still remain in regards to treatment, diagnosis and prognosis.