Publications by authors named "Johanna Von Holdt"

Mine dust has been linked to the development of pneumoconiotic diseases such as silicosis and coal workers' pneumoconiosis. Currently, it is understood that the physicochemical and mineralogical characteristics drive the toxic nature of dust particles; however, it remains unclear which parameter(s) account for the differential toxicity of coal dust. This study aims to address this issue by demonstrating the use of the partial least squares regression (PLSR) machine learning approach to compare the influence of D sub 10 μm coal particle characteristics against markers of cellular damage.

View Article and Find Full Text PDF

Dust models are essential for understanding the impact of mineral dust on Earth's systems, human health, and global economies, but dust emission modelling has large uncertainties. Satellite observations of dust emission point sources (DPS) provide a valuable dichotomous inventory of regional dust emissions. We develop a framework for evaluating dust emission model performance using existing DPS data before routine calibration of dust models.

View Article and Find Full Text PDF
Article Synopsis
  • Dust from mining has led to high levels of diseases like silicosis and coal workers' pneumoconiosis (CWP), with ongoing concerns about CWP worldwide.
  • Current safety measures assume all fine dust is equally harmful, but this is not accurate for coal due to its complex nature.
  • The review suggests a need for better risk assessment strategies that take into account the specific characteristics of coal dust, such as its mineral composition and physical properties, which may influence lung inflammation and disease development.
View Article and Find Full Text PDF

Establishing mineral dust impacts on Earth's systems requires numerical models of the dust cycle. Differences between dust optical depth (DOD) measurements and modelling the cycle of dust emission, atmospheric transport, and deposition of dust indicate large model uncertainty due partially to unrealistic model assumptions about dust emission frequency. Calibrating dust cycle models to DOD measurements typically in North Africa, are routinely used to reduce dust model magnitude.

View Article and Find Full Text PDF