Publications by authors named "Johanna Tolksdorf"
Article Synopsis
- The Eurotransplant kidney allocation system permits unlimited re-transplantation, but the benefits and outcomes remain unclear.
- A 15-year study analyzed data from 1,464 patients undergoing third or higher kidney transplants, finding these recipients were younger and had better HLA matches but did not show improved outcomes.
- Results indicated that mortality, graft loss, and primary nonfunction rates were significantly higher in recipients of third or greater transplants compared to first transplants, prompting a reevaluation of current re-transplantation policies.
Background: Online clinical risk prediction tools built on data from multiple cohorts are increasingly being utilized for contemporary doctor-patient decision-making and validation. This report outlines a comprehensive data science strategy for building such tools with application to the Prostate Biopsy Collaborative Group prostate cancer risk prediction tool.
Methods: We created models for high-grade prostate cancer risk using six established risk factors.