Increased blood coagulation is associated with poor neurological outcome in aneurysmal subarachnoid hemorrhage.

Background And Purpose: Patients with aneurysmal subarachnoid hemorrhage (aSAH) have demonstrated increased blood coagulation which is thought to contribute to delayed cerebral ischemia (DCI) and to a worse outcome. Therefore, we sought to determine whether this increased blood coagulation, detectable with rotational thromboelastometry (ROTEM), was associated with DCI and neurological outcome.

Methods: We conducted a prospective observational study of 60 consecutive adult aSAH patients.

Clinical Characteristics and the Dietary Response in Celiac Disease Patients Presenting With or Without Anemia.

Background And Aims: It remains unclear as to what are the clinical characteristics associated with the presence of anemia at celiac disease diagnosis, and how these are affected by a gluten-free diet. We investigated these issues in a prospective study.

Methods: Clinical and demographic data, small-bowel mucosal histology, serology, and laboratory parameters, body mass index (BMI), and bone mineral density (BMD) both at diagnosis and after 1 year on a gluten-free diet were investigated in 163 adults with celiac disease.