Publications by authors named "Johanna S Salzer"

Article Synopsis
  • * Between July 2023 and January 2024, California reported six RMSF cases linked to exposure in Tecate, Mexico, raising concerns as it was previously not identified as a high-risk area, and three of these cases were fatal.
  • * Effective detection of RMSF cases necessitated collaborative efforts among various public health agencies, highlighting the need for increased awareness among healthcare providers to enable quicker diagnoses and treatments on both sides of the U.S.-Mexico border.
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Objective: Pet ownership among people experiencing homelessness (PEH) is common, but access to shelter, veterinary care, and flea-preventative products for PEH who own pets in the US is not well described. We sought to evaluate current knowledge of fleas and flea-borne diseases and characterize practices around pets and service animals among staff at homeless shelters and outreach organizations.

Methods: In-person surveys were administered to staff at homeless shelters and on outreach teams in 7 states from August 2022 to April 2023 to evaluate knowledge, attitudes, and practices and to assess homeless shelter/organizational characteristics.

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Rocky Mountain spotted fever (RMSF) is a severe tickborne disease that can reach epidemic proportions in communities with certain social and ecologic risk factors. In some areas, the case-fatality rate of brown dog tick-associated RMSF is up to 50%. Because of the spread of brown dog tick-associated RMSF in the southwestern United States and northern Mexico, the disease has the potential to emerge and become endemic in other communities that have large populations of free-roaming dogs, brown dog ticks, limited resources, and low provider awareness of the disease.

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Article Synopsis
  • * A scientific symposium held from November 8-10, 2023, brought together experts from academia and health authorities to discuss RMSF challenges and potential solutions.
  • * The One Health approach is emphasized as a key strategy to enhance surveillance, diagnosis, and prevention efforts to combat RMSF effectively in Mexico.
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  • Anthrax, caused by the bacterium Bacillus anthracis, is a significant zoonotic disease in livestock and humans, especially in Karnataka, India, necessitating a better understanding of its outbreaks.
  • The study aims to analyze the relationship between anthrax outbreaks from 1987-2016 and climatic factors, using advanced statistical methods to develop predictive models for public health and vaccination strategies.
  • Findings indicate that anthrax outbreaks are positively influenced by rainfall and wet days, with a long-term cycle of 6-8 years linked to Sea Surface Temperature anomalies, highlighting the importance of climate in prevention efforts.
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  • The brown dog tick, Rhipicephalus sanguineus s.l., is a significant carrier of Rickettsia rickettsii, which causes Rocky Mountain spotted fever, prompting public health measures to control tick infestations around homes and on pets.
  • Current control strategies primarily rely on acaricides, particularly synthetic pyrethroids, but many ticks have developed resistance to these chemicals, complicating prevention efforts.
  • Researchers used advanced sequencing techniques to study genetic variations associated with acaricide resistance in different lineages of the tick, finding a specific genetic mutation tied to resistance that was commonly found in tropical lineage ticks across various locations in the US.
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  • Louse-borne Bartonella quintana and flea-borne murine typhus are serious diseases affecting people experiencing homelessness in the US, but service staff's awareness and prevention knowledge is limited.
  • A survey of 333 staff from 89 shelters across seven states revealed that while most recognize the problem of body lice and fleas, only about half understand their disease transmission potential, and less than 25% can describe proper management protocols.
  • There are significant gaps in understanding among staff regarding these diseases, highlighting the need for training to improve prevention efforts and ensure equitable service access for affected individuals.
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Background: Alpha-gal syndrome (AGS) is an allergy to galactose-α-1,3-galactose (alpha-gal), a carbohydrate found in most mammals. Evidence indicates that AGS develops after a tick bite, and in the United States, AGS is most associated with bites from Amblyomma americanum (lone star tick); however, not all persons bitten by ticks develop clinical AGS.

Objective: To investigate intrinsic risk factors associated with the development of AGS.

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We obtained samples from the Department of Defense Serum Repository from soldiers who were stationed at Fort Liberty, North Carolina, between 1991 and 2019 to assess temporal trends in tick-borne rickettsiosis and ehrlichiosis. Serological evidence of infection was common, with nearly 1 in 5 (18.9%) demonstrating antibodies.

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Brucellosis is a zoonotic disease, caused by some species within the Brucella genus. The primary and secondary objectives of this cross-sectional study were to determine the seroprevalence of Brucella antibodies in humans and cows and identify risk factors for exposure to Brucella spp. among people in Shahjadpur sub-district, Bangladesh.

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Melioidosis, caused by , is a rare but potentially fatal bacterial disease endemic to tropical and subtropical regions worldwide. It is typically acquired through contact with contaminated soil or fresh water. Before this investigation, was not known to have been isolated from the environment in the continental United States.

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Alpha-gal syndrome (AGS) is an emerging, tick bite-associated immunoglobulin E-mediated allergic condition characterized by a reaction to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal), which is found in mammalian meat and products derived from mammals, including milk, other dairy products, and some pharmaceutical products. Symptoms range from mild (e.g.

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Alpha-gal syndrome (AGS) is an emerging, tick bite-associated allergic condition characterized by a potentially life-threatening immunoglobulin E (IgE)-mediated hypersensitivity to galactose-alpha-1,3-galactose (alpha-gal), an oligosaccharide found in most nonprimate mammalian meat and products derived from these mammals. Specific symptoms and severity of AGS vary among persons, and no treatment or cure is currently available. During 2010-2018, more than 34,000 suspected cases of AGS were identified in the United States, but current knowledge of where cases occur is limited.

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Burkholderia thailandensis, an opportunistic pathogen found in the environment, is a bacterium closely related to B. pseudomallei, the cause of melioidosis. Human B.

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Article Synopsis
  • In November 2020, Missouri introduced a modified quarantine policy for K-12 students with low-risk exposures to COVID-19, allowing them to continue in-person learning while assessing the impacts of quarantine on students and families.
  • A survey sent to parents of 586 students revealed that only 11% engaged in modified quarantine, with 46% of them avoiding non-school activities compared to 72% of those in standard home quarantine.
  • Students in modified quarantine experienced less stress and fewer negative impacts on family life than those in standard quarantine, suggesting that the modified approach could effectively balance educational needs and COVID-19 prevention.
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Data on monkeypox in children and adolescents aged <18 years are limited (1,2). During May 17–September 24, 2022, a total of 25,038 monkeypox cases were reported in the United States, primarily among adult gay, bisexual, and other men who have sex with men (3). During this period, CDC and U.

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Article Synopsis
  • * A CDC report analyzed 57 hospitalized monkeypox patients from August to October 2022, revealing that 82% had HIV, most were male (95%), and 68% were non-Hispanic Black; 30% needed ICU care, and 21% died due to severe symptoms.
  • * Health care providers are advised to test sexually active monkeypox patients for HIV and consider aggressive treatment for those who are severely immunocompromised
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Objective: To determine whether modified K-12 student quarantine policies that allow some students to continue in-person education during their quarantine period increase schoolwide SARS-CoV-2 transmission risk following the increase in cases in winter 2020-2021.

Methods: We conducted a prospective cohort study of COVID-19 cases and close contacts among students and staff (n = 65,621) in 103 Missouri public schools. Participants were offered free, saliva-based RT-PCR testing.

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Article Synopsis
  • In August 2022, a nurse in Florida contracted monkeypox from a patient while on the job, marking the first reported case in the U.S. related to occupational exposure.
  • Cases of monkeypox among healthcare personnel have been uncommon during the 2022 multinational outbreak.
  • The report emphasizes the need for preventive measures to protect healthcare workers from acquiring monkeypox in the workplace.
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Since May 2022, approximately 20,000 cases of monkeypox have been identified in the United States, part of a global outbreak occurring in approximately 90 countries and currently affecting primarily gay, bisexual, and other men who have sex with men (MSM) (1). Monkeypox virus (MPXV) spreads from person to person through close, prolonged contact; a small number of cases have occurred in populations who are not MSM (e.g.

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Melioidosis is an underreported human disease of tropical and sub-tropical regions caused by the saprophyte Burkholderia pseudomallei. Although most global melioidosis cases are reported from tropical regions in Southeast Asia and northern Australia, there are multiple occurrences from sub-tropical regions, including the United States (U.S.

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  • Group bacteria with anthrax toxin genes can lead to deadly anthrax pneumonia in welders.
  • Two cases from 2020 were investigated to find the source of exposure, involving environmental sampling of soil and dust at the patients' worksites.
  • The investigation revealed that while one patient's samples showed positive results for anthrax toxins, including matching the patient's clinical isolate, the other patient's samples tested negative, highlighting the importance of workplace assessments to reduce exposure risks.
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  • Classroom layout is crucial for maintaining physical distance in schools to prevent COVID-19 transmission during in-person learning.
  • A study measured and analyzed 90 classrooms in Missouri, assessing distances between students, teachers, and potentially infectious individuals.
  • Results showed that limited physical distancing (less than 6 feet) did not lead to increased COVID-19 transmission among students before the Delta variant surge, suggesting a way to optimize classroom capacity while safely supporting in-person education.
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  • * The paper reviews literature on this illness, termed "welder's anthrax," detailing epidemiology, including two specific cases from 2020.
  • * It discusses health risks linked to welding, mechanisms of infection, prevention strategies, and the importance of controlling exposure to welding fumes to reduce disease transmission in the workplace.
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  • A study explored the preference for saliva-based COVID-19 testing over nasal swabs among K-12 students, parents, teachers, and staff in Missouri schools during a surveillance investigation.
  • Out of 719 participants surveyed, over one-third who accepted the saliva test would have declined a nasal swab, with 51% of elementary school students (or their guardians) indicating a preference for saliva.
  • The findings suggest that implementing saliva testing could enhance participation in COVID-19 screening in schools, potentially aiding in controlling the spread of the virus.
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