Aim: This study aimed to assess and compare the fracture resistance of endodontically treated teeth using three new intraorifice barrier materials.
Materials And Methods: A total of 60 extracted human mandibular premolars having single roots were decoronated to 14 mm length, prepared up to rotary F3 ProTaper Gold files, and sealed with gutta-percha and AH Plus sealer. Specimens were divided into one control and three experimental groups ( = 15): Group 1, control; Group 2, Biodentine (Septodont, Saint Maur des Fosses, France); Group 3, resin-modified glass ionomer cement (RMGIC, GC Gold Label 2 LC, GC Corporation, Tokyo, Japan); and Group 4, flowable nanohybrid composite (G-aenial Universal Flo, GC Corporation, Tokyo, Japan).