Publications by authors named "Johana Almansa"

Objectives: This study sought to determine the efficacy and safety of a novel, pH-neutral formulation of furosemide administered subcutaneously (SC) for treatment of acute decompensated heart failure (HF).

Background: Congestion requiring intravenous (IV) administration of a diuretic agent is the main reason patients with HF present for acute medical care.

Methods: Outpatients presenting with decompensated HF were randomized to receive a single SC or IV dose of furosemide.

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Article Synopsis
  • Amyloidosis involves a buildup of amyloid deposits in tissues, with ATTR amyloidosis being a notable subtype that can occur with or without specific genetic mutations.
  • Diagnosis typically involves a tissue biopsy followed by advanced testing techniques like liquid chromatography tandem mass spectrometry (LC-MS/MS) to identify the amyloid type, but genetic testing may also be necessary.
  • A study found that while LC-MS/MS identified mutations in 84% of patients with biopsy-confirmed ATTR amyloidosis, it missed several key mutations, highlighting the importance of genetic testing for accurate diagnosis and treatment planning.
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Background: Recent studies have suggested a high prevalence of cardiac amyloidosis (CAm) in heart failure (HF) patients. CAm might be underdiagnosed owing to low clinical suspicion.

Methods And Results: We performed retrospective analysis of 259 patients with HF and ejection fraction (EF) ≥50% referred for endomyocardial biopsy.

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Background: Heart failure (HF) is a major health care burden and there is a growing need to develop strategies to maintain health and sustain quality of life in persons with HF. The purpose of this review is to critically appraise the components of nutrition interventions and to establish an evidence base for future advances in HF nutrition research and practice.

Methods And Results: Cinahl, Pubmed, and Embase were searched to identify articles published from 2005 to 2015.

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