Publications by authors named "Johan Robbrecht"
Objectives: Rheumatoid factor (RF) is a well-established marker for the diagnosis and classification of rheumatoid arthritis (RA). Most studies evaluated IgM RF or isotype-nonspecific total RF assays. We evaluated the added value of IgA RF in this context.
View Article and Find Full Text PDFIntroduction: Commercial assays measuring antibodies to citrullinated protein/peptide (ACPA) show poor quantitative agreement. The diagnostic industry has never adopted the International Union of Immunological Societies-Centers for Disease Control and Prevention (IUIS-CDC) ACPA reference standard. Recently, the National Institute for Biological Standards and Control (NIBSC) prepared a new candidate ACPA standard (18/204).
View Article and Find Full Text PDFArticle Synopsis
- Researchers studied different tests used to diagnose rheumatoid arthritis (RA) to see how well they worked together.
- They looked at 18 different tests from various companies using samples from patients with RA and others without the disease.
- They found that by setting specific rules for how to read the test results, doctors could better understand and compare the tests, leading to more accurate diagnoses for RA.
Objective: In this study, the performance of 2 commercially available SARS-CoV-2 antibody assays is evaluated.
Methods: The Siemens SARS-CoV-2 Total (COV2T) and IgG (COV2G) antibody tests were evaluated on a Siemens Atellica IM1300 analyzer. Imprecision was assessed with the CLSI EP15 protocol using positive controls.