Publications by authors named "Johan Hellgren"

Background: Chronic rhinosinusitis (CRS) decreases the quality of life and affects the working life of sufferers. There is a scarcity of studies of how CRS affects sick leave at the population level, particularly for women.

Materials And Methods: Data from questionnaires were collected in Telemark, Norway in 2013 (N = 15,484) and again in 2018 (N = 13,966).

View Article and Find Full Text PDF

Background: Flexible rhinolaryngoscopes are an important tool in otolaryngology. In recent years, single-use rhinolaryngoscopes (SURLs), which have been developed as an alternative to reusable scopes (RRLs), offer various advantages including less risk of contamination and elimination of the need for cleaning and reprocessing between procedures. This study aimed to compare procedure efficiency, organizational impact, and economic impact between SURLs and RRLs used for elective procedures conducted outside the otorhinolaryngology department in the hospital environment.

View Article and Find Full Text PDF
Article Synopsis
  • Deep neck space infections (DNSI) are serious conditions that can arise from dental infections and are preventable; this study focuses on their economic impact.
  • A study involving 148 patients found the total cost of illness (COI) due to DNSI to be approximately 15,400 EUR per patient, with direct costs making up 93% of this total.
  • The COI for DNSI was found to be six times greater than that of typical otorhinolaryngology cases, highlighting the need for prevention to save costs and improve patient outcomes.
View Article and Find Full Text PDF

Background: Fatigue is the most debilitating symptom in patients with multiple sclerosis (MS). Natalizumab and rituximab are the most used MS disease modifying therapies in Sweden, but comparative data on the effect on fatigue is sparse.

Objective: Primary objective was to compare fatigue levels between patients on natalizumab and rituximab.

View Article and Find Full Text PDF

Objective: Men represent more than two-thirds of septoplasty patients in many studies, but differences between men and women in terms of patient selection or outcome are seldom reported. This study aims to investigate whether women undergoing septoplasty differ from men in critical variables before and after surgery, in a large national sample of septoplasties.

Design: Cross-sectional register study.

View Article and Find Full Text PDF

Introduction: Orbital trapdoor fractures in children and adolescents can cause persistent problems with vision and appearance. Early surgery is recommended, although, because of the rarity of these fractures, there is a lack of evidence regarding the optimal timing of surgery.The objective of this study was to examine the effect of the time from trauma to surgery on the recovery time and severity of diplopia in children and adolescents with orbital trapdoor fractures.

View Article and Find Full Text PDF

Background: Chronic rhinosinusitis (CRS) is associated with generalised airway inflammation. Few studies have addressed the relationship between CRS and chronic bronchitis (CB).

Methods: This prospective study over a five-year period aims to investigate the risk of developing CB in subjects reporting CRS at the beginning of the study.

View Article and Find Full Text PDF

Purpose: Obesity is a growing, global health problem and previous cross-sectional studies have demonstrated an association between obesity and chronic rhinosinusitis (CRS). There is, however, a lack of prospective studies regarding the impact of obesity on developing (new-onset) CRS.

Methods: Questionnaire-based data (n = 5769) relating to new-onset CRS and Body Mass Index (BMI) were collected in 2013 and 2018 from the Telemark population study in Telemark, Norway.

View Article and Find Full Text PDF

Eosinophils have a broad range of functions, both homeostatic and pathological, mediated through an array of cell surface receptors and specific secretory granules that promote interactions with their microenvironment. Eosinophil development, differentiation, activation, survival and recruitment are closely regulated by a number of type 2 cytokines, including interleukin (IL)-5, the key driver of eosinophilopoiesis. Evidence shows that type 2 inflammation, driven mainly by interleukin (IL)-4, IL-5 and IL-13, plays an important role in the pathophysiology of eosinophilic airway diseases, including asthma, chronic rhinosinusitis with nasal polyps, eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome.

View Article and Find Full Text PDF

Purpose: Humans have a preference for nasal breathing during sleep. This 10-year prospective study aimed to determine if nasal symptoms can predict snoring and also if snoring can predict development of nasal symptoms. The hypothesis proposed is that nasal symptoms affect the risk of snoring 10 years later, whereas snoring does not increase the risk of developing nasal symptoms.

View Article and Find Full Text PDF

Purpose: Sleep-disordered breathing, SDB, in children is associated with morbidity that can result in caregivers having to stay at home from work. The aim of this study was to investigate whether the number of days when caregivers are reimbursed, temporary parental benefit (TPB) to stay at home from work to care for their sick child is increased among children with SDB before and after tonsil surgery.

Methods: This is a retrospective, cross-sectional study of children (n = 440), aged 2-11 years, that underwent tonsil surgery for SDB in day surgery at Sahlgrenska University Hospital in 2014 and 2015.

View Article and Find Full Text PDF

This article describes new Swedish guidelines for the care of adult patients having a tracheostomy. A national expert panel of ENT and anaesthesiology specialists appointed by each national specialist association reviewed fatal patient cases involving tracheostomy failure as well as national and international guidelines to produce a "best of practice" document. The main recommendation is that the health care provider has the full responsibility to ensure that the combined surgical competence at the hospital can handle acute airway problems also under difficult anatomical conditions.

View Article and Find Full Text PDF

Purpose: Chronic obstructive pulmonary disease (COPD) is associated with several co-morbidities and non-infectious rhinitis (NIR) has emerged as a new possible co-morbidity. The primary aim of this study is to confirm a previously reported association between NIR and COPD in a multicentre population over time. The secondary aim is to investigate the course over time of such an association through a comparison between early- and late-onset COPD.

View Article and Find Full Text PDF

Objectives: The use of rituximab (RTX) in multiple sclerosis (MS) is a rapidly increasing choice of disease-modifying therapy. Efficacy outside specialized university hospital-based care is not yet systematically investigated. Our aim was to evaluate off-label RTX treatment for MS at a general hospital in Sweden.

View Article and Find Full Text PDF

Study Objectives: Chronic rhinosinusitis (CRS) is a common inflammatory disease of the nasal cavity and paranasal sinuses. Associations between CRS and poor sleep quality have been reported. This 10-year follow-up study investigates possible associations between incident CRS and sleep quality.

View Article and Find Full Text PDF

At-home respiratory polygraphy has been shown to be a reliable substitute for in-laboratory polysomnography in adults for diagnosing obstructive sleep apnea, but this is less well studied in children. One aim of this study was to examine the quality of at-home respiratory polygraphy in children with sleep-disordered breathing and to evaluate the interrater reliability of the results. Another aim was to study whether calibrated respiratory inductance plethysmography (RIP) flow can be used for the scoring of respiratory events when the airflow measurements are unreliable.

View Article and Find Full Text PDF

Continuous monitoring of the need to educate specialists is important in the planning of health care resources. In this article, the authors present a questionnaire-based tool that is answered by the heads of Departments of ear, nose and throat (ENT) across Sweden every year. In Stockholm, the movement of patients from university to private ENT has dramatically decreased specialist training in ENT, and this can be seen by the employment survey instrument called »Tjänsteenkäten«.

View Article and Find Full Text PDF

Objective: Are patients with symptomatic unilateral maxillary sinusitis sent for a dental evaluation of odontogenic maxillary sinusitis (OMS)?

Patients And Methods: The medical records of all patients diagnosed with sinusitis at a university Ear-nose and throat (ENT) clinic from 2010 to 2015 were scrutinized for symptomatic unilateral maxillary sinusitis verified on CT. Any dental evaluation was recorded, as well as symptoms of OMS, duration to dental evaluation, diagnosis of OMS and dental treatment.

Results: A total of 1338 patients diagnosed with sinusitis were screened; 172 had unilateral maxillary sinusitis and 48% (82/172) OMS.

View Article and Find Full Text PDF

Objective: To study predictors of symptom relief six months after septoplasty using data from the Swedish National Septoplasty Register.

Participants: This is a retrospective register study of adult patients undergoing septoplasty in Sweden in 2003-2012.

Outcome: Relief of nasal symptoms was analysed in relation to age, gender, size of hospital performing the surgery, addition of turbinoplasty, and unplanned postoperative visits to the hospital due to pain, bleeding, or infection.

View Article and Find Full Text PDF

Objective: The aim of this study was to investigate the association between occupational exposure and chronic rhinosinusitis.

Methods: A random population from the region of Telemark, aged 16 to 50 years, answered a respiratory questionnaire including questions on chronic rhinosinusitis and exposure in the occupational environment.

Results: A total of 16,099/48,142 subjects responded.

View Article and Find Full Text PDF

Objective To study the efficacy of budesonide nasal spray on the health-related quality of life and symptoms among children with sleep-disordered breathing. Study Design Randomized, parallel, double-blind, placebo-controlled trial. Setting Tertiary referral center.

View Article and Find Full Text PDF

Objective/background: Little is known about associations between traffic exposure and sleep disturbances. We examined if self-reported exposure to traffic is associated with habitual snoring and daytime sleepiness in a general population.

Methods: In the RHINE III study, 12184 adults answered questions on sleep disturbances and traffic exposure.

View Article and Find Full Text PDF

Background: The aim of this population-based study was to investigate the risk of developing noninfectious rhinitis (NIR) in subjects with chronic obstructive pulmonary disease (COPD).

Materials And Methods: This is a longitudinal population-based study comprising 3,612 randomly selected subjects from Gothenburg, Sweden, aged 25-75 years. Lung function was measured at baseline with spirometry and the included subjects answered a questionnaire on respiratory symptoms.

View Article and Find Full Text PDF

Allergic rhinitis is the most common form of allergy with a prevalence of 30%. Allergic rhinitis is associated with substantial health economic costs and patient suffering. Asthma is strongly associated with allergic rhinitis.

View Article and Find Full Text PDF

This article presents the guidelines for the treatment of epistaxis in an out-patient setting in Sweden. Nasal hemorrhage from the anterior part of the nasal cavity is best treated with silver nitrate cauterization or electrocautery. Bleeding from the posterior part of the nasal cavity often requires treatment with a pneumatic nasal tamponade, RapidRhino, or a posterior nasal packing with a Foley catheter.

View Article and Find Full Text PDF