Publications by authors named "Johan H Reiber"
Article Synopsis
- This study investigates how to predict suboptimal quantitative flow ratios (QFR) after successful PCI, as current models are lacking in this area.
- The researchers created a nomogram using data from 450 vessels to evaluate the prediction based on five key variables, including a new metric called QFR-PPG.
- Results showed strong predictive performance with high accuracy in different validation tests, highlighting the nomogram's potential to aid clinicians in making informed decisions post-PCI.
Echocardiography-derived hemodynamic forces (HDF) allow calculation of intraventricular pressure gradients from routine transthoracic echocardiographic images. The evolution of HDF after cardiac resynchronization therapy (CRT) has not been investigated in large cohorts. The aim was to assess HDF in patients with heart failure implanted with CRT versus healthy controls.
View Article and Find Full Text PDFAims: In chronic coronary syndrome (CCS) patients with documented coronary artery disease (CAD), ischaemia detection by myocardial perfusion imaging (MPI) and an invasive approach are viable diagnostic strategies. We compared the diagnostic performance of quantitative flow ratio (QFR) with single-photon emission computed tomography (SPECT), positron emission tomography (PET), and cardiac magnetic resonance imaging (CMR) in patients with prior CAD [previous percutaneous coronary intervention (PCI) and/or myocardial infarction (MI)].
Methods And Results: This PACIFIC-2 sub-study evaluated 189 CCS patients with prior CAD for inclusion.
Risk stratification of patients with ischemic heart disease (IHD) still depends mainly on the left ventricular ejection fraction (LVEF). LV inward displacement (InD) is a novel parameter of LV systolic function, derived from feature tracking cardiac magnetic resonance (CMR) imaging. We aimed to investigate the prognostic impact of InD in patients with IHD and prior myocardial infarction.
View Article and Find Full Text PDFBackground: Advances in coronary computed tomography angiography (CCTA) reconstruction algorithms are expected to enhance the accuracy of CCTA plaque quantification. We aim to evaluate different CCTA reconstruction approaches in assessing vessel characteristics in coronary atheroma using intravascular ultrasound (IVUS) as the reference standard.
Methods: Matched cross-sections (n = 7241) from 50 vessels in 15 participants with chronic coronary syndrome who prospectively underwent CCTA and 3-vessel near-infrared spectroscopy-IVUS were included.
Article Synopsis
- * This trial will involve 2,540 participants randomized to receive either PCI guided by QFR or standard care, utilizing a specific stent that allows for shorter anti-clotting therapy post-procedure.
- * The primary goal is to see if QFR-guided PCI is as effective as usual care in preventing major cardiac events within one year, with follow-ups lasting up to three years.
Objectives: This study compared the performance of the quantitative flow ratio (QFR) with single-photon emission computed tomography (SPECT) and positron emission tomography (PET) myocardial perfusion imaging (MPI) for the diagnosis of fractional flow reserve (FFR)-defined coronary artery disease (CAD).
Background: QFR estimates FFR solely based on cine contrast images acquired during invasive coronary angiography (ICA). Head-to-head studies comparing QFR with noninvasive MPI are lacking.
Objectives: To determine the most relevant aerodynamic characteristic of the oropharynx related to the collapse of the upper airway in obstructive sleep apnea (OSA) patients; and to determine the correlation between the most relevant aerodynamic characteristic(s) of the oropharynx and anatomical characteristics of the oropharynx in OSA patients.
Methods: 31 mild to moderate OSA patients (mean ± SD age = 43.5 ± 9.
Population based ultrasonographic screening of abdominal aortic aneurysms.
Int J Cardiovasc Imaging
November 2016
Article Synopsis
- The study focuses on developing an automated method to extract the aorto-femoral vessel trajectory using computed tomography angiography (CTA) for trans-catheter aortic valve replacement (TAVR).
- An automatic vessel tracking algorithm identifies the centerline between the femoral and aortic points, followed by a 3D-model fitting method to outline the vascular path in a CTA dataset.
- Validation against results from two experienced observers shows high agreement in vessel segmentation and measurements, indicating the effectiveness of the automated method.
Aim: To investigate the efficacy of low-density lipoprotein (LDL) transport simulation in reconstructed arteries derived from computed tomography coronary angiography (CTCA) to predict coronary segments that are prone to progress.
Methods And Results: Thirty-two patients admitted with an acute coronary event who underwent 64-slice CTCA after percutaneous coronary intervention and at 3-year follow-up were included in the analysis. The CTCA data were used to reconstruct the coronary anatomy of the untreated vessels at baseline and follow-up, and LDL transport simulation was performed in the baseline models.
Background: Total atherosclerotic plaque burden assessment by CT angiography (CTA) is a promising tool for diagnosis and prognosis of coronary artery disease (CAD) but its validation is restricted to small clinical studies. We tested the feasibility of semi-automatically derived coronary atheroma burden assessment for identifying patients with hemodynamically significant CAD in a large cohort of patients with heterogenous characteristics.
Methods: This study focused on the CTA component of the CORE320 study population.
Introduction And Objectives: The Absorb bioresorbable vascular scaffold has been shown to decrease total plaque areas in the treated segment. However, it is unknown whether plaque size is modified in scaffolded segments only or whether the modification extends to other coronary segments.
Methods: Absorb Cohort A is a single-arm, prospective study, with safety and imaging endpoints, in which 30 patients underwent percutaneous coronary intervention with the first generation Absorb bioresorbable vascular scaffold.