Synopsis of recent research by authors named "Johan Ericson"
- Johan Ericson's recent research primarily focuses on the differentiation of neural stem cells and the mechanisms underlying the development of various neuronal types, particularly dopamine neurons, as well as the impact of transcription factors on these processes.
- Key findings highlight the importance of retinoic acid signaling in deriving mesencephalic dopamine neurons from human pluripotent stem cells, and the establishment of a Shh/Gli-driven timer that governs the temporal identity of neural stem cells.
- Ericson's work also emphasizes the functional roles of transcription factors like Lmx1a, Lmx1b, and SOX proteins in neuron specification and overall neural cell fate determination, contributing significantly to our understanding of neurogenesis and potential therapeutic applications for neurodegenerative diseases.
