Publications by authors named "Joerg Kunte"

Article Synopsis
  • Halomonas elongata, a halophilic bacterium, primarily synthesizes ectoine to adapt to salty environments and can also absorb it from its surroundings using the osmoregulated transporter TeaABC.
  • Disrupting TeaABC leads to a strain that loses ectoine, but the mechanism behind ectoine export remains unclear.
  • The bacterium has four mscS genes linked to small conductance mechanosensitive channels, which are down-regulated in high salinity; mutants lacking these genes grow faster in high salt but still export 80% of ectoine, suggesting an alternative export system exists.
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Zearalenone (ZEN) and its phase II sulfate and glucoside metabolites have been detected in food and feed commodities. After consumption, the conjugates can be hydrolyzed by the human intestinal microbiota leading to liberation of ZEN that implies an underestimation of the true ZEN exposure. To include ZEN conjugates in routine analysis, reliable standards are needed, which are currently not available.

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Ectoine plays an important role in protecting biomolecules and entire cells against environmental stressors such as salinity, freezing, drying and high temperatures. Recent studies revealed that ectoine also provides effective protection for human skin cells from damage caused by UV-A radiation. These protective properties make ectoine a valuable compound and it is applied as an active ingredient in numerous pharmaceutical devices and cosmetics.

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