Nuclear morphometry and chromatin texture changes in hepatocellular carcinoma samples may predict outcomes of liver transplanted patients.

Background: Nuclear changes are typical in the carcinogenesis of hepatocellular carcinoma (HCC). Morphometry and chromatin texture analysis are quantitative methods for their quantification. In this study, we analyzed nuclear morphometry and chromatin texture parameters in samples of hepatocellular carcinoma from liver transplant patients and their associations with clinicopathologic variables.

The gene expression of GPER1 is low in fresh samples of papillary thyroid carcinoma (PTC), and in silico analysis.

Papillary thyroid cancer (PTC), whose incidence has been increasing in the last years, occurs more frequently in women. Experimental studies suggested that estrogen could be an important risk factor for the higher female incidence. In fact, it has been demonstrated that 17β-estradiol (E2) could increase proliferation and dedifferentiation in thyroid follicular cells.

Effects of the composite nanovesicles on the physical properties and cellular adhesion of chitosan films.

Chitosan films were prepared by the casting of a chitosan gel in absence and presence of composite nanovesicles. The microscopy images showed the occurrence of agglomerates on the surface and internal pores when the nanovesicles were added to the films, differently from the smooth surface of the pure chitosan films. Despite the hydrophobic character that composite nanovesicles gave to the chitosan films, as showed by the reduction of the water permeation at prolonged times, there was a reduction on the contact angle values for these samples related to the roughness of the surface.