Publications by authors named "Joelle A Pettus"
Article Synopsis
- * Researchers found that while most children had normal neurodevelopmental scores, a significant number displayed issues, especially as they grew older; specific factors like low birth weight and maternal education influenced outcomes.
- * The findings suggest that children with sTOF may have elevated developmental concerns, and although the type of surgical intervention didn't seem to affect these outcomes, other risks like genetic syndromes are important to consider for early intervention.
Article Synopsis
- - The study analyzed neonates with symptomatic tetralogy of Fallot (sTOF) to examine how hypoplastic pulmonary arteries (hPA) impact survival and treatment outcomes, reviewing data from 2005 to 2017 on 542 cases.
- - Results showed that while reintervention was more common in the hPA group, survival rates and mortality did not differ significantly between those with hPA and those with normal pulmonary arteries.
- - Notably, the hPA cohort experienced better pulmonary artery growth after one year, suggesting that having hPA does not negatively affect the overall outcomes for neonates with sTOF.
Article Synopsis
- Neonates with tetralogy of Fallot and pulmonary atresia rely on the arterial duct for blood flow and require early surgical intervention, either through primary repair or staged repair, but the best method remains unclear.* -
- A review of 282 neonates revealed that while mortality rates were similar between primary and staged repair, those undergoing staged repair faced greater early reintervention rates and had larger conduit sizes during complete repair.* -
- Primary repair generally showed better outcomes in terms of lower complications, shorter hospital stays, and better growth of the right pulmonary artery, while staged repair is more common in patients with greater risk factors such as DiGeorge syndrome.*
Objective: To evaluate early growth following primary or staged repair of neonatal symptomatic tetralogy of Fallot (sTOF).
Study Design: We performed a retrospective, multicenter cohort study of consecutive infants with sTOF who underwent initial intervention at age ≤30 days, from 2005 to 2017. Management strategies were either primary repair or staged repair (ie, initial palliation followed by complete repair).
Background: Multicentre research databases can provide insights into healthcare processes to improve outcomes and make practice recommendations for novel approaches. Effective audits can establish a framework for reporting research efforts, ensuring accurate reporting, and spearheading quality improvement. Although a variety of data auditing models and standards exist, barriers to effective auditing including costs, regulatory requirements, travel, and design complexity must be considered.
View Article and Find Full Text PDFBackground: Neonates with tetralogy of Fallot and symptomatic cyanosis (sTOF) require early intervention.
Objectives: This study sought to perform a balanced multicenter comparison of staged repair (SR) (initial palliation [IP] and subsequent complete repair [CR]) versus primary repair (PR) treatment strategies.
Methods: Consecutive neonates with sTOF who underwent IP or PR at ≤30 days of age from 2005 to 2017 were retrospectively reviewed from the Congenital Cardiac Research Collaborative.
Clinical research in the treatment of patients with congenital heart disease (CHD) is limited by the wide variety of CHD manifestations and therapeutic options as well as the generally low incidence of CHD. The availability of comprehensive, contemporary outcomes studies is therefore limited. This inadequacy may result in a lack of data-driven medical decision making.
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