Winning with Losses: The Surprising Success of Negative Strategies in Social Interaction Behavior.

In the vast network of social interactions and behaviors, it is common to find certain schemes that, on their own, might appear counterproductive to societal progress. When observed in isolation, these schemes often seem to hinder more than they help. However, due to society's complexity, the hidden potential of combining these seemingly detrimental schemes often goes unnoticed.

A comprehensive framework for preference aggregation Parrondo's paradox.

Individuals can make choices for themselves that are beneficial or detrimental to the entire group. Consider two losing choices that some individuals have to make on behalf of the group. Is it possible that the losing choices combine to give a winning outcome? We show that it is possible through a variant of Parrondo's paradox-the preference aggregation Parrondo's paradox (PAPP).

Extending the Lifespan of Multicellular Organisms via Periodic and Stochastic Intercellular Competition.

Resolution of the intrinsic conflict between the reproduction of single cells and the homeostasis of a multicellular organism is central to animal biology and has direct impact on aging and cancer. Intercellular competition is indispensable in multicellular organisms because it weeds out senescent cells, thereby increasing the organism's fitness and delaying aging. In this Letter, we describe the growth dynamics of multicellular organisms in the presence of intercellular competition and show that the lifespan of organisms can be extended and the onset of cancer can be delayed if cells alternate between competition (a fair strategy) and noncompetitive growth, or cooperation (a losing strategy).

A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway.

One common cause of vision loss after retinal detachment surgery is the formation of proliferative and contractile fibrocellular membranes. This aberrant wound healing process is mediated by epithelial-mesenchymal transition (EMT) and hyper-proliferation of retinal pigment epithelial (RPE) cells. Current treatment relies primarily on surgical removal of these membranes.

Decision-making psychology and method under zero-knowledge context.

For a certain kind of decision event, the decision maker does not know the internal mechanism and knowledge information of the decision events.When this kind of decision events gives multiple selection branches, it is found that there is a decision psychological tendency to find the most common features by comparing the selection branches. Based on this, a zero-knowledge decision making (ZKDM) method is proposed.

Antiangiogenic Nanomicelles for the Topical Delivery of Aflibercept to Treat Retinal Neovascular Disease.

The traditional intravitreal injection delivery of antivascular endothelial growth factor (anti-VEGF) to the posterior segment of the eye for treatment of retinal diseases is invasive and associated with sight-threatening complications. To avoid such complications, there has been significant interest in developing polymers for topical drug delivery to the retina. This study reports a nanomicelle drug delivery system made of a copolymer EPC (nEPCs), which is capable of delivering aflibercept to the posterior segment topically through corneal-scleral routes.

Schizophrenia: A Survey of Artificial Intelligence Techniques Applied to Detection and Classification.

Artificial Intelligence in healthcare employs machine learning algorithms to emulate human cognition in the analysis of complicated or large sets of data. Specifically, artificial intelligence taps on the ability of computer algorithms and software with allowable thresholds to make deterministic approximate conclusions. In comparison to traditional technologies in healthcare, artificial intelligence enhances the process of data analysis without the need for human input, producing nearly equally reliable, well defined output.

Relieving Cost of Epidemic by Parrondo's Paradox: A COVID-19 Case Study.

COVID-19, also known as SARS-CoV-2, is a coronavirus that is highly pathogenic and virulent. It spreads very quickly through close contact, and so in response to growing numbers of cases, many countries have imposed lockdown measures to slow its spread around the globe. The purpose of a lockdown is to reduce reproduction, that is, the number of people each confirmed case infects.

Superposition of COVID-19 waves, anticipating a sustained wave, and lessons for the future.

The 2019 coronavirus (COVID-19), also known as SARS-CoV-2, is highly pathogenic and virulent, and it spreads very quickly through human-to-human contact. In response to the growing number of cases, governments across the spectrum of affected countries have adopted different strategies in implementing control measures, in a hope to reduce the number of new cases. However, 5 months after the first confirmed case, countries like the United States of America (US) seems to be heading towards a trajectory that indicates a health care crisis.

Parrondo paradoxical walk using four-sided quantum coins.

Two losing games can be played in a certain manner to produce a winning outcome-a phenomenon known as Parrondo's paradox. Of particular interest is the emergence of quantum game theory and the attempt to model known Parrondo's games through quantum computation notation. In this article, we investigate whether flipping four-sided quantum coins will result in the emergence of Parrondo's paradox.

Parrondo effect in quantum coin-toss simulations.

Game A + Game B = Game C. Parrondo's games follow this basic structure where A and B are losing games and C is a winning game-a phenomenon called Parrondo's paradox. These games can take on a wider class of definitions and exhibit these paradoxical results.

Acute Health Impacts of the Southeast Asian Transboundary Haze Problem-A Review.

Air pollution has emerged as one of the world's largest environmental health threats, with various studies demonstrating associations between exposure to air pollution and respiratory and cardiovascular diseases. Regional air quality in Southeast Asia has been seasonally affected by the transboundary haze problem, which has often been the result of forest fires from "slash-and-burn" farming methods. In light of growing public health concerns, recent studies have begun to examine the health effects of this seasonal haze problem in Southeast Asia.