Publications by authors named "Joel N Eliason"
Article Synopsis
- Immune checkpoint inhibitor (ICI) therapy shows promise for non-small cell lung cancer (NSCLC) patients with high PD-L1 expression, but not all patients respond effectively.
- * This study uses multiplex fluorescent immunohistochemistry (mfIHC) to analyze 1,269 images from 52 metastatic NSCLC patients, identifying key interactions between tumor cells and immune cells that may predict treatment response.
- * The research uncovers specific spatial patterns, like increased activity of cytotoxic and helper T-cells in responders, and introduces a deep learning model that identifies crucial cellular regions influencing therapy outcomes.*
