Perinatal risk factors for fecal antibiotic resistance gene patterns in pregnant women and their infants.

Perinatal factors can shape fecal microbiome patterns among pregnant women and their infants. However, there is scarce information about the effect of maternal demographics and perinatal exposures on antibiotic resistance genes (ARG) and mobile genetic element (MGE) patterns in pregnant women and infants. We examined fecal samples from pregnant women during their third trimester of pregnancy (n = 51) and 6-month-old infants (n = 40).

Documenting clinical performance problems among medical students: feedback for learner remediation and curriculum enhancement.

Introduction: We operationalized the taxonomy developed by Hauer and colleagues describing common clinical performance problems. Faculty raters pilot tested the resulting worksheet by observing recordings of problematic simulated clinical encounters involving third-year medical students. This approach provided a framework for structured feedback to guide learner improvement and curricular enhancement.

High correlations in gene expression between paired umbilical cord blood and neonatal blood of healthy newborns on Guthrie cards.

Objective: To examine the correlation in genes expressed in paired umbilical cord blood (UCB) and newborn blood (NB).

Method: Total mRNA and mRNA of three gene sets (inflammatory, hypoxia, and thyroidal response) was assessed using microarray in UCB and NB spotted on Guthrie cards from 7 mother/infant pairs.

Results: The average gene expression correlation between paired UCB and NB samples was 0.

Breast cancer and cervical cancer control program enrollees inform the kin keeper curriculum.

Background: The purpose of this study is to present the methodology of developing the Kin Keeper Cancer Prevention Curriculum Guide and Workbook through participatory engagement of women from underserved communities.

Methods: It was developed to cross train community health workers (CHWs) from public health programs to deliver cancer education. Data collection included review of existing educational materials, a 10-minute telephone survey of 146 women enrolled in a Breast and Cervical Cancer Control Program and a pair of pre-post training assessments of 31 African American, Latina, and Arab CHWs.

Family history of cancer predicts Papanicolaou screening behavior for African American and white women.

Background: Understanding women's motivations for getting Papanicolaou (Pap) screening has the potential to impact cancer disparities. This study examined whether having a family history of cancer was a predictor for Pap screening.

Methods: By using the National Health Interview Survey 2000 Cancer Control and Family modules, we identified a subsample (n=15,509) of African American (n=2774) and white women (n=12,735) unaffected by cancer, with and without a family history of cancer.