Pharmacokinetics and pharmacodynamics of enrofloxacin and a low dose of amikacin administered via regional intravenous limb perfusion in standing horses.

Objective: To evaluate the pharmacokinetic-pharmacodynamic parameters of enrofloxacin and a low dose of amikacin administered via regional IV limb perfusion (RILP) in standing horses.

Animals: 14 adult horses.

Procedures: Standing horses (7 horses/group) received either enrofloxacin (1.

Septic arthritis, tenosynovitis, and infections of hoof structures.

Infectious diseases of synovial and hoof structures in horses can be devastating to soundness and can result in life-threatening complications. Timely diagnosis and early aggressive treatment can result in successful outcomes and resumption of athletic careers; however, delays in recognition and therapy can be the most costly reasons for failure. Sterilization of affected compartments and tissues requires removal of microorganisms and compromised tissue.

Airway inflammation is associated with mucous cell metaplasia and increased intraepithelial stored mucosubstances in horses.

This study was performed to determine if a peripheral sample of lung from the site where biopsy is conducted is representative of the rest of the lung and to investigate the relationship between airway inflammation and intraepithelial mucous production in the peripheral airways. Lung parenchyma samples were collected from five different regions of the lung in five control and five heaves-affected horses. Horse groups were defined by clinical response to stabling.

Use of a condylar screw plate for repair of a Salter-Harris type-III fracture of the femur in a 2-year-old horse.

A 2-year-old sexually intact male Paint horse weighing 427 kg (940 lb) was admitted for examination and treatment of intermittent non-weight-bearing lameness of the right hind limb of 1 week's duration. Radiography revealed a displaced Salter-Harris type-III fracture of the right femoral condyle with the sagittal component of the fracture line located in the intercondylar space and the transverse component exiting on the medial aspect of the femur. The fracture was repaired with a condylar screw plate designed for repair of femoral condylar fractures in humans.

Safety and efficacy of a technique for thoracoscopically guided pulmonary wedge resection in horses.

Objective: To evaluate the safety and efficacy of thoracoscopically guided pulmonary wedge resection in horses.

Animals: 10 horses (5 control horses and 5 horses affected with recurrent airway obstruction [ie, heaves]).

Procedure: Each horse underwent a thoracoscopically guided pulmonary wedge resection.