Psoralen Isolated from the Roots of Welw. Modulate Th1/Th2 Cytokines and Inflammatory Enzymes in LPS-Stimulated RAW 264.7 Macrophages.

is a widely used plant spice in traditional African medicine to treat pain-related conditions. However, the anti-inflammatory mechanisms underlying this activity and the main active ingredients of have not yet been fully characterized. This study aimed to isolate and identify the main active anti-inflammatory constituents of the extract and to investigate the underlying anti-inflammatory mechanisms in murine macrophages.

Antibacterial constituents of spreng and its emodin derivatives.

The CHCl-MeOH (1:1) extract of roots of (Polygonaceae) displayed significant antibacterial activity against five bacterial strains with MICs (62.5-31.2 μg.