Publications by authors named "Joel Dekoven"
Article Synopsis
- - The study analyzed contact allergies to peppermint (MP) oil using data from the North American Contact Dermatitis Group, finding that out of 28,128 patients tested, only 161 (0.6%) exhibited an allergic reaction.
- - The majority of allergic patients were female (77%) and over 40 years old (71.4%), with common dermatitis locations being the face (31.7%), hands (17.4%), and generalized areas (18.6%).
- - A significant number (30.4%) experienced strong to extreme reactions, primarily linked to products like oral hygiene items, foods, and lip products; many also had co-reactions with other fragrance allergens, indicating that around 40% of cases
Article Synopsis
- Photoallergic contact dermatitis (PACD) is a hypersensitivity reaction triggered by allergens only when exposed to UV light, requiring photopatch testing (PhotoPT) for diagnosis.* -
- A study from 2009-2020 involving 454 patients revealed that most were women, aged 21-60, and the majority were White; results showed 119 positive tests, predominantly related to sunscreen agents like benzophenones.* -
- Among the diagnosed conditions, approximately 17.2% of patients had PACD, while other diagnoses included allergic contact dermatitis, polymorphous light eruption, and chronic actinic dermatitis, highlighting the need for photopatch testing in these cases.*
Construction workers (CWs) are at risk for occupational contact dermatitis (CD) owing to workplace exposures. Determine the prevalence of occupational allergic CD and characterize common occupational allergens in CWs referred for patch testing in the United States and Canada. Retrospective cross-sectional analysis of patients patch tested by the North American Contact Dermatitis Group from 2001 to 2020.
View Article and Find Full Text PDFDoubtful patch test reactions generally do not meet criterion for positivity in patch testing. However, the North American Contact Dermatitis Group (NACDG) allows for doubtful reactions to be coded with a final determination of "allergic/positive" based on the temporal pattern, appearance, known characteristics of the allergen, and/or other supportive patch test reactions. To analyze NACDG data from the 2019-2020 patch test cycle to identify patterns in the interpretation and relevance of doubtful reactions.
View Article and Find Full Text PDFAllergic contact dermatitis is frequently caused by metals, including multiple metals simultaneously. To assess characteristics and associations of positive and clinically relevant patch test (PT) reactions with solitary and concurrent metal sensitization. A retrospective analysis of PT results for nickel, cobalt, and/or chromium from the North American Contact Dermatitis Group between 2001 and 2018 ( = 43,522).
View Article and Find Full Text PDFBackground: Isothiazolinones are a common cause of allergic contact dermatitis.
Objective: To examine the prevalence of positive patch test reactions to isothiazolinones from 2017-2020 and characterize isothiazolinone-allergic (Is+) patients compared with isothiazolinone nonallergic (Is-) patients.
Methods: Retrospective cross-sectional analysis of 9028 patients patch tested to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) 0.
Allergic contact Dermatitis® (ACD) in older adults (OA) represents a significant health burden, but few studies examine the prevalence and characteristics of contact allergy and ACD in this population. To compare positive and clinically relevant patch test results in OA versus younger adults (YA) and children. Retrospective analysis of patch test results obtained in OA (≥65 years), YA (19-64 years), and children (≤18 years) by the North American Contact Dermatitis® Group, 2009 to 2020.
View Article and Find Full Text PDFParaphenylenediamine (PPD) is an aromatic amine dye that may cause allergic contact dermatitis. This study examines the epidemiology of allergic patch test reactions to PPD. This retrospective analysis characterizes individuals tested to PPD (1% petrolatum) by the North American Contact Dermatitis Group (1994-2018).
View Article and Find Full Text PDFChlorhexidine is an antiseptic that may cause allergic contact dermatitis. To describe the epidemiology of chlorhexidine allergy and characterize positive patch test reactions. This retrospective study analyzed patients patch tested to chlorhexidine digluconate 1% aqueous by the North American Contact Dermatitis Group, 2015-2020.
View Article and Find Full Text PDFCobalt is a recognized cause of allergic contact dermatitis (ACD); however, detailed information on patient characteristics, sites, and sources is lacking. The aim of the study is to assess trends in patch test reactions to cobalt and associated patient characteristics, common sources, and body sites affected. The study used a retrospective analysis of adult patients who were patch tested to cobalt by the North American Contact Dermatitis Group between 2001 and 2018 (n = 41,730).
View Article and Find Full Text PDFBenzophenone (BZP)-3 and BZP-4 are ultraviolet (UV) absorbers used in sunscreens and personal care products (PCPs) and may cause allergic contact dermatitis. To characterize positive patch test reactions to BZP-3 (10% in petrolatum [pet]) and BZP-4 (2% pet) in a screening allergen series. Retrospective analysis of patients tested to BZP-3 and BZP-4 was conducted by the North American Contact Dermatitis Group from 2013 to 2020.
View Article and Find Full Text PDFPatch testing is an important diagnostic tool for assessment of allergic contact dermatitis (ACD). This study documents the North American Contact Dermatitis Group (NACDG) patch testing results from January 1, 2019, to December 31, 2020. At 13 centers in North America, patients were tested in a standardized manner with a screening series of 80 allergens, and, as indicated, supplemental allergens.
View Article and Find Full Text PDFArticle Synopsis
- * Data was collected from several databases and showed that while positivity rates for MCI/MI have decreased in Europe, they have continued to rise in North America, especially for MI.
- * The differing trends in reactions could be linked to earlier and stricter regulations on MI in Europe compared to North America.
Article Synopsis
- An updated understanding of allergic contact cheilitis is necessary, as it shows increasing prevalence across a study period from 2001 to 2018.
- A retrospective analysis of over 43,000 patients revealed that about 4.8% had lips involved in dermatitis, with a notable rise in cases documented in later years.
- The study found high rates of positive allergic reactions among patients with cheilitis, suggesting the importance of including a broader range of allergens in patch testing, especially those beyond standard NACDG screening.
Background: Dermatitis localized to hands (HD), feet (FD), or both hands and feet (HFD) has multiple etiologies, including atopic dermatitis, irritant contact dermatitis, and allergic contact dermatitis. Unfortunately, little is known about clinical differences between patients with HD, FD, and HFD.
Objective: To characterize differences in demographics, etiology, and patch testing results among patients presenting with HD, FD, or HFD referred for patch testing.
Background: Allergic contact dermatitis (ACD) to cobalt is more common in children and adolescents than adults. However, detailed information on sites and sources of cobalt ACD is limited.
Objectives: To assess trends in positive and clinically relevant patch test reactions to cobalt in children and associated patient characteristics, common sources and body sites affected.
Article Synopsis
- - Alkyl glucosides, used in personal care products, were tested for allergic reactions; among 24,097 patients, 2.0% showed positive patch test reactions.
- - Positive reactions were more common in individuals with occupational skin disease, hay fever, atopic dermatitis, and asthma, with most reactions linked to hair and skin cleansing products.
- - Cross-reactivity between decyl and lauryl glucosides was significant, with over 40% of patients sensitive to both types, indicating relevant clinical implications.
Background: Lanolin is an important cause of allergic contact dermatitis.
Objectives: The aims of this study were to describe the epidemiology of lanolin allergy and to assess trends in patch test reactions to lanolin over time.
Methods: This study used a retrospective analysis of patients patch tested with lanolin alcohol 30% or Amerchol L-101 50% in petrolatum by the North American Contact Dermatitis Group between 2001 and 2018 (n = 43,691).
Background: Dental personnel are at risk of developing occupational contact dermatitis.
Objectives: The aims of the study were to determine prevalence of occupational contact dermatitis in dental personnel referred for patch testing and to characterize relevant allergens and sources.
Methods: The study used a retrospective, cross-sectional analysis of the North American Contact Dermatitis Group (NACDG) data, 2001-2018.
Background: Shoe contact allergy can be difficult to diagnose and manage.
Objective: The aim of the study was to characterize demographics, clinical characteristics, patch test results, and occupational data for the North American Contact Dermatitis Group patients with shoe contact allergy.
Methods: This is a retrospective study of 33,661 patients, patch tested from 2005 to 2018, with a shoe source, foot as 1 of 3 sites of dermatitis, and final primary diagnosis of allergic contact dermatitis.