Impact of cord entanglement on perinatal outcome.

Objective: To evaluate the impact of umbilical cord entanglement around various fetal organs on perinatal outcomes.

Study Design: A retrospective population-based study of all deliveries between 1988 and 2016 at a tertiary medical center. Immediate perinatal outcomes of newborns with and without cord entanglement were compared.

S100B in maternal circulation of pregnancies complicated by FGR and brain sparing.

Objective: To determine whether the presence of brain sparing in fetal growth restricted (FGR) fetuses involves elevation of the cerebral injury biomarker S100B in maternal circulation.

Methods: We included 63 women with suspected small for gestational age (SGA) fetuses between 24 and 35 +6/7 weeks of gestation. Maternal plasma angiogenic factors measurements and sonographic evaluation were performed at recruitment.

Estimation of fetal weight using Hadlock's formulas: Is head circumference an essential parameter?

Objectives: To test the equivalence of two fetal weight estimation formulas generated by Hadlock, a formula that includes head circumference parameter (H1), and another (H2) which excludes this parameter. A secondary aim was to identify the patients in which H2 formula is less reliable to use.

Study Design: This retrospective cohort study included a total of 1220 sonographic fetal weight estimations performed within seven days of delivery and recorded at a single medical center from January 2014 to December 2016.

Fetal wide subarachnoid space and its outcome in cases of macrocephaly without ventriculomegaly.

To examine the occurrence and outcomes of fetuses with wide subarachnoid space (WSS) without ventriculomegaly in pregnant women with fetal macrocephaly as a sole diagnosis. A retrospective study was performed, analyzing patients with fetal macrocephaly between the years 2008 and 2018. All these patients underwent MRI, in order to detect brain anomalies.

The risk of placenta accreta following primary cesarean delivery.

Objective: To (a) evaluate the risk for placenta accreta following primary cesarean section (CS), in regard to the stage of labor, the cesarean section was taken (elective prelabor vs. unplanned during labor); and (b) investigate whether the association between placenta accreta and maternal and neonatal complications is modified by the type of the primary CS.

Study Design: In a population-based retrospective cohort study, we included all singleton deliveries occurred in Soroka University Medical Center between 1991 and 2015, of women who had a history of a single CS.

Sonographic large fetal head circumference and risk of cesarean delivery.

Background: Persistently high rates of cesarean deliveries are cause for concern for physicians, patients, and health systems. Prelabor assessment might be refined by identifying factors that help predict an individual patient's risk of cesarean delivery. Such factors may contribute to patient safety and satisfaction as well as health system planning and resource allocation.

Dilated cerebral venous system observed in growth-restricted fetuses.

Purpose: The dilation of the fetal cerebral veins is a rare phenomenon that may be associated to a bad obstetric outcome, and is usually connected to antenatal thrombosis of the posterior dural venous sinuses. There are several descriptions of cerebral vein distension on magnetic resonance imaging (MRI), but all of them are detected postnatally. We present herein two cases of fetal antenatal cerebral dilation of the venous system, without any association to any sign of vein thrombosis, and a systematic review of literature regarding pathogenesis, diagnosis and outcomes associated to the antenatal detection of this condition with the use of MRI.

Ultrasonographic approach to diagnosis of fetal inflammatory response syndrome: a tool for at-risk fetuses?

Preterm parturition is a syndrome that may result from many underlying mechanisms. Infection and inflammation are the prominent ones. Intrauterine infection and inflammation have an effect akin to sepsis, and that is similar to systemic inflammatory response in adults.

Postpartum uterine artery blood flow impedance following cesarean section or vaginal delivery.

Purpose: To compare uterine arteries (UtA) blood flow after cesarean section (CS) or vaginal delivery (VD).

Methods: We performed a prospective case-control study comparing UtA blood flow impedance in patients who delivered by CS or VD. The UtA pulsatility index (PI) was measured with Doppler ultrasound during post partum using a transabdominal convex probe.

The significance of a uterine rupture in subsequent births.

Objective: To determine whether women with a previous uterine rupture have a higher risk of adverse perinatal outcome in subsequent births.

Methods: A retrospective study comparing all subsequent singleton cesarean deliveries (CD) of women with a previous uterine rupture, with CD of women with no such history, during the years 1988-2011 was conducted.

Results: Out of 34,601 singleton CD that occurred during the study period, 0.

The effect of non-obstetric invasive procedures during pregnancy on perinatal outcomes.

Purpose: To evaluate the effect of non-obstetric invasive procedure during pregnancy on perinatal outcome.

Methods: The present retrospective study investigated perinatal outcome in women that underwent an invasive procedure during one of their pregnancies (n = 61); perinatal outcome was compared to other pregnancies (without an invasive procedure) of the same patients (n = 122).

Results: Women with a non-obstetric invasive procedure during pregnancy delivered earlier than those in the comparison group (38.

Antenatal diagnosis of idiopathic arterial calcification: a systematic review with a report of two cases.

Introduction: Idiopathic antenatal calcification is a rare, generally lethal, condition with unclear etiology.

Materials And Methods: Around 200 cases, most of them undergoing postnatal diagnosis, are reported in literature. The majority of the affected infants die before the age of 6 months, and very few have survived for more than 1 year.

Umbilical artery blood flows among pregnancies with single umbilical artery: a prospective case-control study.

Objectives: To evaluate peak systolic velocity (PSV) in the umbilical artery (UA) among patients with single umbilical artery (SUA) as compared with patients with three vessel cords.

Methods: A prospective case-control study was performed. UA blood flow velocimetry was obtained from fetuses with SUA and from a control group with three vessel cord.

Blood flow Doppler velocimetry measured during active labor.

Purpose: To evaluate blood flow Doppler velocimetry during the first and second stages of active labor.

Methods: A prospective observational study was performed. Patients at term (37-42 weeks gestation), with normal fetal heart rate tracing patterns (categorized as category I) were examined during the first and second stages of labor.

Diminished activity of circulating α1-antitrypsin is associated with pre-gestational isolated obesity.

Objective: To examine possible correlation between α1-antitrypsin (AAT) levels and activity in patients with and without obesity, after excluding complications such as gestational diabetes mellitus (GDM), during pregnancy.

Study Design: A prospective case-control study was conducted. AAT levels were determined by standard human AAT ELISA according to the manufacturer's instructions.

The consequences of previous uterine scar dehiscence and cesarean delivery on subsequent births.

Objective: To determine whether women with a previous uterine scar dehiscence are at increased risk of adverse perinatal outcomes in the following delivery.

Methods: A retrospective cohort study was conducted of all subsequent singleton cesarean deliveries performed at the Soroka University Medical Center, Beer-Sheva, Israel, between January 1, 1988, and December 31, 2011. Clinical and demographic characteristics, maternal obstetric complications, and fetal complications were evaluated among women with or without a previous documented uterine scar dehiscence.

Postpartum uterine artery Doppler velocimetry among patients following a delivery complicated with preeclampsia.

Objective: To evaluate postpartum uterine artery (UtA) velocimetry in patients following severe preeclampsia (PET) as compared with normotensive controls.

Study Design: Postpartum UtA velocimetry was obtained prospectively during the early postpartum period. The right and left UtA pulsatility index (PI) was measured and the presence of an early diastolic notch was noted.

A Live Birth Subsequent to IVF following Egg Retrieval Only 12 Hours after hCG Priming.

Introduction. To report a live birth following egg retrieval after only 12 hours from hCG priming. Patients.

Low levels of circulating alpha-1 antitrypsin are associated with spontaneous abortions.

Objective: Alpha-1 antitrypsin (AAT), a circulating anti-inflammatory molecule, rises four- to sixfold during acute phase responses and during pregnancy. AAT deficiency is linked with various pregnancy complications. The aim of this study is to determine plasma concentrations and activity of AAT and serum cytokine levels in blood samples from women undergoing spontaneous abortions as compared with elective abortions.

Lower circulation levels and activity of α-1 antitrypsin in pregnant women with severe preeclampsia.

Objective: α-1 antitrypsin (AAT) is an anti-protease, anti-inflammatory and tissue-protective molecule. Normal circulating levels are <3.5 mg/dl and rise during pregnancy.

α1-antitrypsin insufficiency is a possible contributor to preterm premature rupture of membranes.

Objective: α1-antitrypsin (AAT) is protective of tissue damage induced by enzymes of inflammatory cell source. Inflammatory cells are involved in preterm labor, preterm premature rupture of membrane (PPROM) and term premature rupture of membrane (PROM). The purpose of this research was to examine whether plasma concentration and activity of AAT differ between these manifestations.

Spontaneous pneumothorax in the third trimester of pregnancy.

The present report concerns a young woman previously diagnosed as having childhood asthma who presented with a secondary spontaneous pneumothorax during the third trimester of pregnancy; at term a caesarean section was recommended for safety reasons. Post partum a severe fixed ventilatory defect unresponsive to inhaled bronchodilator and a short oral course of steroids ruled out asthma. Diffuse bronchiectasis was found on her chest CT scan, although this was not evident clinically.